Biological characteristics of IL-6 and related intestinal diseases.
Biological characteristics of IL-6 and related intestinal diseases.
复制标题
IL-6生物学特性与相关肠道疾病
DOI:
10.7150/ijbs.51362
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发表时间:
2021
影响因子:
9.2
通讯作者:
Xu JD
中科院分区:
文献类型:
--
作者:
Guo Y;Wang B;Wang T;Gao L;Yang ZJ;Wang FF;Shang HW;Hua R;Xu JD
The intestine serves as an important digestive and the largest immune organ in the body. Interleukin-6(IL-6), an important mediator of various pathways, participates in the interactions between different kinds of cells and closely correlates with intestinal physiological and pathological condition. In this review we summarize the signaling pathways of IL-6 and its functions in maintaining intestinal homeostasis. We also explored its relation with nervous system and highlight its potential role in Parkinson's disease. Based on its specialty of the double-side influences on intestinal tumors and inflammation, we summarize how they are done through distinctive process.
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影响因子:
64.8
作者:
Bettelli, E;Carrier, YJ;Kuchroo, VK
通讯作者:
Kuchroo, VK
影响因子:
2.6
作者:
Abhari, Fatemeh Mahdavi;Pirestani, Majid;Dalimi, Abdolhossein
通讯作者:
Dalimi, Abdolhossein
影响因子:
3.8
作者:
Comini, L;Pasini, E;Ferrari, R
通讯作者:
Ferrari, R
影响因子:
5.5
作者:
Buckley, Maria M.;O'Halloran, Ken D.;O'Malley, Dervla
通讯作者:
O'Malley, Dervla
影响因子:
4.9
作者:
BAQAR, S;PACHECO, ND;ROLLWAGEN, FM
通讯作者:
ROLLWAGEN, FM