INCIDENCE OF YOUNG ONSET INSULIN-REQUIRING DIABETES MELLITUS AMONG 18- TO 30-YEAR-OLDS IN DHAKA, BANGLADESH (1994−2003)
INCIDENCE OF YOUNG ONSET INSULIN-REQUIRING DIABETES MELLITUS AMONG 18- TO 30-YEAR-OLDS IN DHAKA, BANGLADESH (1994−2003)
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孟加拉国达卡 18 至 30 岁青年中发病的胰岛素需求型糖尿病发病率（1994−2003 年）
DOI：
10.18999/nagjms.74.1-2.149
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发表时间：
2012
影响因子：
0.9
通讯作者：
T. Nakajima
中科院分区：
文献类型：
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作者：
Saika Nizam;M. Khalequzzaman;H. Yatsuya;Khanam Pa;Sayeed Ma;Hisao Naito;T. Nakajima
摘要 关于年轻发病的胰岛素需求型糖尿病 (IRDM) 的流行病学信息很少。我们描述了孟加拉国达卡男性和女性年轻发病 IRDM 的发病率及其趋势。随后，调查了与可能的性别差异相关的因素。年轻发病的IRDM被定义为18-30岁的糖尿病患者，需要三个月或更长时间的胰岛素治疗，但没有出现酮尿。 1994年至2003年间，登记了1,804起案件。发病率根据2001年人口普查用分母计算。1994-2003年期间年轻发病IRDM的总体年发病率为每10万人8.5人（95% CI：7.2-7.9），女性相应值为（每10万人10.9人，95% CI： 9.2-12.1）高于男性（每 10 万人 6.7，95% CI 5.6-7.9）。在调查期间，女性的发病率显着增加，但男性则没有（性别相互作用的 p < 0.01）。 1994-1998年和1999-2003年间，体重指数≥25.0 kg/m2（超重/肥胖）的女性病例增幅明显高于男性（3个百分点）（19个百分点）（性别互动p<0.01）。达卡市女性中年轻发病的 IRDM 发病率正在增加，这是由于超重/肥胖女性病例的增加。
ABSTRACT Little information is available regarding the epidemiology of young onset insulin-requiring diabetes mellitus (IRDM). We described the incidence of young onset IRDM and its trend in males and females of Dhaka, Bangladesh. Subsequently, factors related to possible sex difference were investigated. Young onset IRDM was defined as diabetic patients aged 18–30 years who required three months or more insulin treatment but presented no ketonuria. Between 1994 to 2003, 1,804 cases were registered. Incidence rates were calculated with denominators based on the population census 2001. The overall annual incidence of young onset IRDM for the period 1994–2003 was 8.5 per 100,000 persons (95% CI: 7.2–7.9), and the corresponding value for females (10.9 per 100,000 persons, 95% CI: 9.2–12.1) was higher than that in males (6.7 per 100,000 persons, 95% CI 5.6–7.9). The incidence rate significantly increased in females during the investigated period, but not in males (p for sex interaction < 0.01). There was a significantly higher increment of female cases with a body mass index ≥ 25.0 kg/m2 (overweight/obesity) (19 percentage point) compared to that of males (3 percentage point) between 1994–1998 and 1999–2003 (p for sex interaction < 0.01). The incidence of young onset IRDM is increasing in the Dhaka City population among females, which is attributed to the increase in overweight/obese female cases.
DOI：
10.1007/bf02801872
发表时间：
1986-12
期刊：
International Journal of Pancreatology
影响因子：
--
作者：
R. Dani;F. J. Penna;C. Nogueira
通讯作者：
R. Dani;F. J. Penna;C. Nogueira