miRTRAP, a computational method for the systematic identification of miRNAs from high throughput sequencing data.
miRTRAP, a computational method for the systematic identification of miRNAs from high throughput sequencing data.
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DOI:
10.1186/gb-2010-11-4-r39
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发表时间:
2010
期刊:
影响因子:
12.3
通讯作者:
Shi W
中科院分区:
文献类型:
--
作者:
Hendrix D;Levine M;Shi W
A novel method for prediction of miRs from deep sequencing data. Its utility is demonstrated when applied to Ciona data. MicroRNAs (miRs) have been broadly implicated in animal development and disease. We developed a novel computational strategy for the systematic, whole-genome identification of miRs from high throughput sequencing information. This method, miRTRAP, incorporates the mechanisms of miR biogenesis and includes additional criteria regarding the prevalence and quality of small RNAs arising from the antisense strand and neighboring loci. This program was applied to the simple chordate Ciona intestinalis and identified nearly 400 putative miR loci.
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影响因子:
12.3
作者:
Chen X;Li Q;Wang J;Guo X;Jiang X;Ren Z;Weng C;Sun G;Wang X;Liu Y;Ma L;Chen JY;Wang J;Zen K;Zhang J;Zhang CY
通讯作者:
Zhang CY
影响因子:
7
作者:
Hill, Matthew M.;Broman, Karl W.;Sidow, Arend
通讯作者:
Sidow, Arend
影响因子:
10.5
作者:
Babiarz, Joshua E.;Ruby, J. Graham;Blelloch, Robert
通讯作者:
Blelloch, Robert
影响因子:
5.8
作者:
Langenberger, David;Bermudez-Santana, Clara;Stadler, Peter F.
通讯作者:
Stadler, Peter F.
影响因子:
2.1
作者:
Liu, Jin-Gang;Shibasaki, Yuji;Ueda, Mitsuru
通讯作者:
Ueda, Mitsuru