Effects of potassium on blood pressure in salt-sensitive and salt-resistant black adolescents.

Effects of potassium on blood pressure in salt-sensitive and salt-resistant black adolescents.
复制标题

钾对盐敏感和耐盐黑人青少年血压的影响。

DOI:
10.1161/01.hyp.34.2.181
复制
发表时间:
1999
期刊:
Hypertension (Dallas, Tex. : 1979)
影响因子:
--
通讯作者:
Miller,SB
Miller,SB
中科院分区:
--
文献类型:
--
作者:
Wilson,DK;Sica,DA;Miller,SB

文献摘要

参考文献

被引文献

相似文献

- 这项研究考察了增加膳食钾对盐敏感和耐盐黑人青少年动态血压非下降状态(从清醒到睡眠血压下降<10%)和心血管反应性的影响。58名血压正常(血压,101/57±9/4 mm Hg)的黑人青少年(年龄13至16岁)参加了为期5天的低钠饮食(50 mmol/24 h),然后是为期10天的高钠饮食(150 mmol/24 h NaCl补充),以确定盐敏感性状态。参与者的尿钠排泄量显著增加(24±19至224±65 mmol/24 h),如果从低钠饮食到高钠饮食的平均血压升高≥5 mm Hg,则被确定为盐敏感性。然后将16名盐敏感和42名耐盐受试者随机分配到为期3周的高钾饮食(80 mmol/24 h)或常规饮食对照组。治疗组的尿钾排泄量显著增加(35±7至57±21 mmol/24 h)。在基线时,盐敏感者(44%)与盐抵抗者(7%)相比,在舒张压分类的基础上,显着更大的百分比是非勺型(P<0.04)。饮食干预后,高钾组中所有盐敏感受试者的夜间舒张压下降(白天,69与67 mm Hg;夜间,69与57 mm Hg),从而达到了杓型状态。未观察到心血管反应性的显著组间差异。这些结果表明,即使白天的血压不受高钾饮食的影响,膳食钾摄入量和血压调节之间的正相关关系仍然存在。
—This study examined the effects of increasing dietary potassium on ambulatory blood pressure nondipping status (<10% decrease in blood pressure from awake to asleep) and cardiovascular reactivity in salt-sensitive and salt-resistant black adolescents. A sample of 58 normotensive (blood pressure, 101/57±9/4 mm Hg) black adolescents (aged 13 to 16 years) participated in a 5-day low sodium diet (50 mmol/24 h) followed by a 10-day high sodium diet (150 mmol/24 h NaCl supplement) to determine salt-sensitivity status. Participants showed a significant increase in urinary sodium excretion (24±19 to 224±65 mmol/24 h) and were identified as salt-sensitive if their mean blood pressure increase was ≥5 mm Hg from the low to high sodium diet. Sixteen salt-sensitive and 42 salt-resistant subjects were then randomly assigned to either a 3-week high potassium diet (80 mmol/24 h) or usual diet control group. Urinary potassium excretion significantly increased in the treatment group (35±7 to 57±21 mmol/24 h). At baseline, a significantly greater percentage of salt-sensitive (44%) compared with salt-resistant (7%) subjects were nondippers on the basis of diastolic blood pressure classifications (P<0.04). After the dietary intervention, all of the salt-sensitive subjects in the high potassium group achieved dipper status as a result of a drop in nocturnal diastolic blood pressure (daytime, 69 versus 67 mm Hg; nighttime, 69 versus 57 mm Hg). No significant group differences in cardiovascular reactivity were observed. These results suggest that a positive relationship between dietary potassium intake and blood pressure modulation can still exist even when daytime blood pressure is unchanged by a high potassium diet.
患有轻度原发性高血压的黑人患者补充钾的安慰剂对照试验
DOI: --
发表时间: 1989
期刊:
影响因子: --
作者:
Obel Ao
通讯作者: Obel Ao
轻度高血压患者长期口服钾补充剂的对照试验。
DOI: --
发表时间: 1987
影响因子: --
作者:
Alfonso Siani;Pasquale Strazzullo;Litterio Russo;Sergio Guglielmi;L. Iacoviello;Aldo Ferrara;Mario Mancini
通讯作者: Mario Mancini
患有边缘性高血压的年轻患者对 Mg2 的血管舒张反应减弱。
DOI: --
发表时间: 1990
期刊: Circulation
影响因子: 37.8
作者:
T. Fujita;Y. Ito;K. Ando;Hiroshi Noda;E. Ogata
通讯作者: E. Ogata
DOI: 10.1161/01.hyp.10.4.437
发表时间: 1987
期刊: Hypertension (Dallas, Tex. : 1979)
影响因子: --
作者:
Miller,JZ;Weinberger,MH;Christian,JC
通讯作者: Christian,JC
DOI: --
发表时间: 1982
期刊: The Lancet
影响因子: --
作者:
K. Khaw;S. Thom
通讯作者: S. Thom