Effects of potassium on blood pressure in salt-sensitive and salt-resistant black adolescents.
Effects of potassium on blood pressure in salt-sensitive and salt-resistant black adolescents.
复制标题
钾对盐敏感和耐盐黑人青少年血压的影响。
DOI:
10.1161/01.hyp.34.2.181
复制
发表时间:
1999
期刊:
影响因子:
--
通讯作者:
Miller,SB
中科院分区:
文献类型:
--
作者:
Wilson,DK;Sica,DA;Miller,SB
—This study examined the effects of increasing dietary potassium on ambulatory blood pressure nondipping status (<10% decrease in blood pressure from awake to asleep) and cardiovascular reactivity in salt-sensitive and salt-resistant black adolescents. A sample of 58 normotensive (blood pressure, 101/57±9/4 mm Hg) black adolescents (aged 13 to 16 years) participated in a 5-day low sodium diet (50 mmol/24 h) followed by a 10-day high sodium diet (150 mmol/24 h NaCl supplement) to determine salt-sensitivity status. Participants showed a significant increase in urinary sodium excretion (24±19 to 224±65 mmol/24 h) and were identified as salt-sensitive if their mean blood pressure increase was ≥5 mm Hg from the low to high sodium diet. Sixteen salt-sensitive and 42 salt-resistant subjects were then randomly assigned to either a 3-week high potassium diet (80 mmol/24 h) or usual diet control group. Urinary potassium excretion significantly increased in the treatment group (35±7 to 57±21 mmol/24 h). At baseline, a significantly greater percentage of salt-sensitive (44%) compared with salt-resistant (7%) subjects were nondippers on the basis of diastolic blood pressure classifications (P<0.04). After the dietary intervention, all of the salt-sensitive subjects in the high potassium group achieved dipper status as a result of a drop in nocturnal diastolic blood pressure (daytime, 69 versus 67 mm Hg; nighttime, 69 versus 57 mm Hg). No significant group differences in cardiovascular reactivity were observed. These results suggest that a positive relationship between dietary potassium intake and blood pressure modulation can still exist even when daytime blood pressure is unchanged by a high potassium diet.
登录
查看更多内容
DOI:
--
发表时间:
1989
期刊:
影响因子:
--
作者:
Obel Ao
通讯作者:
Obel Ao
影响因子:
--
作者:
Alfonso Siani;Pasquale Strazzullo;Litterio Russo;Sergio Guglielmi;L. Iacoviello;Aldo Ferrara;Mario Mancini
通讯作者:
Mario Mancini
影响因子:
37.8
作者:
T. Fujita;Y. Ito;K. Ando;Hiroshi Noda;E. Ogata
通讯作者:
E. Ogata
DOI:
10.1161/01.hyp.10.4.437
发表时间:
1987
期刊:
Hypertension (Dallas, Tex. : 1979)
影响因子:
--
作者:
Miller,JZ;Weinberger,MH;Christian,JC
通讯作者:
Christian,JC
DOI:
--
发表时间:
1982
期刊:
The Lancet
影响因子:
--
作者:
K. Khaw;S. Thom
通讯作者:
S. Thom