Astrocytes as active participants of glutamatergic function and regulators of its homeostasis.
Astrocytes as active participants of glutamatergic function and regulators of its homeostasis.
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星形胶质细胞作为谷氨酸能功能的积极参与者及其稳态的调节者。
DOI：
10.1007/978-1-4615-4685-6_6
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发表时间：
1999
影响因子：
--
通讯作者：
A. Volterra
中科院分区：
文献类型：
--
作者：
P. Bezzi;S. Vesce;P. Panzarasa;A. Volterra
传统上，神经胶质细胞被认为是神经元发育、功能和存活的支持元件。然而，最近的研究结果正在修改这一观点，表明胶质细胞也发挥动态作用，积极参与突触功能和大脑中的信息处理。星形胶质细胞是CNS中最丰富的神经胶质细胞类型，与神经细胞密切相关，并且它们的过程通常包裹突触特化（Pfrieger和Barres，1996）。它们的质膜被赋予多种特异性转运蛋白，其摄取突触释放的神经递质如谷氨酸和GABA并严格控制它们的细胞外浓度（例如参见Chaudry et al.，1995年）。
Traditionally, glial cells have been considered as supportive elements for neuronal development, function, and survival. However, recent findings are modifying this view, suggesting that glia plays also dynamic roles and actively participates in synaptic function and processing of information in the brain. Astrocytes, the most abundant type of glia in the CNS, are intimately interconnected with nerve cells, and their processes often enwrap synaptic specializations (Pfrieger and Barres, 1996). Their plasma membranes are endowed with a variety of specific transporter proteins which take up synaptically released neurotransmitters such as glutamate and GABA and tightly control their extracellular concentration (e.g. see Chaudry et al., 1995).
影响因子：
158.5
作者：
ROTHSTEIN, JD;MARTIN, LJ;KUNCL, RW
通讯作者：
KUNCL, RW
影响因子：
56.9
作者：
CORNELLBELL, AH;FINKBEINER, SM;SMITH, SJ
通讯作者：
SMITH, SJ
影响因子：
56.9
作者：
MALMBERG, AB;YAKSH, TL
通讯作者：
YAKSH, TL