A New Megastigmane Alkaloid from Pachysandra terminalis with Antitumor Metastasis Effect
A New Megastigmane Alkaloid from Pachysandra terminalis with Antitumor Metastasis Effect
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一种具有抗肿瘤转移作用的巨柱花生物碱
DOI:
10.1007/s10600-015-1267-y
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发表时间:
2015-03
影响因子:
0.8
通讯作者:
De-Xin Kong,
中科院分区:
文献类型:
--
作者:
Mei-Na Jin;Sheng-Nan Ma;Hui-Yuan Zhai;Nan-Qin;Hong-Quan Duan;De-Xin Kong,
9-(N,N-Dimethyl)-4,7-megastigmedien-3-one (1) was isolated from Pachysandra terminalis and identified by 1D and 2D NMR spectroscopic and mass spectrometric methods. Compound 1 revealed significant anti-metastasis effect on cancer cell migration and invasion through suppressing the expressions of p-PKCζ and p-integrin β1 in human breast cancer cells, and also showed anti-angiogenic activity on human umbilical vein endothelial cells.
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影响因子:
5.1
作者:
Chang, LC;Bhat, KPL;Kinghorn, AD
通讯作者:
Kinghorn, AD
DOI:
10.3891/acta.chem.scand.32b-0391
发表时间:
1979-02
期刊:
Acta Chemica Scandinavica
影响因子:
--
作者:
D. Behr;I. Wahlberg;T. Nishida;C. Enzell;T. Matsuno
通讯作者:
D. Behr;I. Wahlberg;T. Nishida;C. Enzell;T. Matsuno
影响因子:
6.1
作者:
Chen, Yu-Jen;Tsai, Yin-Meng;Liao, Hui-Fen
通讯作者:
Liao, Hui-Fen
影响因子:
64.5
作者:
Etienne-Manneville, S;Hall, A
通讯作者:
Hall, A
影响因子:
3.4
作者:
Wu, Jing;Zhang, Baogang;Zhang, Ning
通讯作者:
Zhang, Ning