The Impact of Host Abundance on the Epidemiology of Tick-Borne Infection.

The Impact of Host Abundance on the Epidemiology of Tick-Borne Infection.
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DOI:
10.1007/s11538-023-01133-8
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发表时间:
2023-03-09
影响因子:
3.5
通讯作者:
--
中科院分区:
数学4区
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--
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由于地理范围的扩大和蜱媒传染因子丰度的增加,蜱媒疾病是日益增加的全球公共卫生问题。蜱传疾病影响增加的一个可能解释是蜱虫数量增加,这可能与它们赖以为生的宿主密度增加有关。在这项研究中,我们开发了一个模型框架,以了解宿主密度,蜱虫人口统计学和蜱传病原体流行病学之间的联系。我们的模型将特定蜱虫阶段的发展与它们赖以为生的特定宿主联系起来。我们发现,主机社区组成和主机密度有蜱虫种群动态的影响,这对主机和蜱的流行病学动态的影响。一个关键的结果是,我们的模型框架可以表现出变化的主机感染流行率为一个固定的密度的一种主机类型,由于密度的变化,其他主机类型,支持不同的蜱生命阶段。我们的研究结果表明,宿主群落组成可能在解释现场观察到的宿主蜱传感染患病率变化方面发挥至关重要的作用。在线版本包含补充材料,可通过10.1007/s11538-023-01133-8获得。
Tick-borne diseases are an increasing global public health concern due to an expanding geographical range and increase in abundance of tick-borne infectious agents. A potential explanation for the rising impact of tick-borne diseases is an increase in tick abundance which may be linked to an increase in density of the hosts on which they feed. In this study, we develop a model framework to understand the link between host density, tick demography and tick-borne pathogen epidemiology. Our model links the development of specific tick stages to the specific hosts on which they feed. We show that host community composition and host density have an impact on tick population dynamics and that this has a consequent impact on host and tick epidemiological dynamics. A key result is that our model framework can exhibit variation in host infection prevalence for a fixed density of one host type due to changes in density of other host types that support different tick life stages. Our findings suggest that host community composition may play a crucial role in explaining the variation in prevalence of tick-borne infections in hosts observed in the field. The online version contains supplementary material available at 10.1007/s11538-023-01133-8.
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