Inhibition of thyroid hormone transport in plasma of rats by polychlorinated biphenyls.
Inhibition of thyroid hormone transport in plasma of rats by polychlorinated biphenyls.
复制标题
多氯联苯对大鼠血浆中甲状腺激素转运的抑制作用。
DOI:
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发表时间:
1989
期刊:
影响因子:
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通讯作者:
A. Brouwer
中科院分区:
文献类型:
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作者:
A. Brouwer
In this study the mechanism of thyroid hormone reductions reported in rodents, following exposure to TCDD (Potter et al, 1983), PCBs (Grassle and Biesmann 1982; Brouwer 1987) and polybrominated biphenyls (Gupta et al 1983), was investigated in rats at the level of the transport protein, transthyretin (TTR), using 3,4,3’,4’-tetrachlorobiphenyl (TCB) as a model compound. Moreover, the effects of a commercial mixture of PCBs, Aroclor 1254, on plasma thyroid hormone concentrations was investigated in rats, in order to predict whether similar alterations would possibly occur in wildlife species, following environmental exposure to PCBs.
影响因子:
7.3
作者:
Pedersen,LG;Darden,TA;Oatley,SJ;McKinney,JD
通讯作者:
McKinney,JD
影响因子:
3.8
作者:
Potter,CL;Sipes,IG;Russell,DH
通讯作者:
Russell,DH