Design and validation of a multi-task, multi-context protocol for real-world gait simulation.
Design and validation of a multi-task, multi-context protocol for real-world gait simulation.
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用于现实步态模拟的多任务多任务的多任务，多上下文协议。
DOI：
10.1186/s12984-022-01116-1
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发表时间：
2022-12-16
影响因子：
5.1
通讯作者：
Mazza, Claudia
中科院分区：
文献类型：
--
作者：
Scott, Kirsty;Bonci, Tecla;Salis, Francesca;Alcock, Lisa;Buckley, Ellen;Gazit, Eran;Hansen, Clint;Schwickert, Lars;Aminian, Kamiar;Bertuletti, Stefano;Caruso, Marco;Chiari, Lorenzo;Sharrack, Basil;Maetzler, Walter;Becker, Clemens;Hausdorff, Jeffrey M.;Vogiatzis, Ioannis;Brown, Philip;Del Din, Silvia;Eskofier, Bjoern;Paraschiv-Ionescu, Anisoara;Keogh, Alison;Kirk, Cameron;Kluge, Felix;Mico-Amigo, Encarna M.;Mueller, Arne;Neatrour, Isabel;Niessen, Martijn;Palmerini, Luca;Sillen, Henrik;Singleton, David;Ullrich, Martin;Vereijken, Beatrix;Froehlich, Marcel;Brittain, Gavin;Caulfield, Brian;Koch, Sarah;Carsin, Anne-Elie;Garcia-Aymerich, Judith;Kuederle, Arne;Yarnall, Alison;Rochester, Lynn;Cereatti, Andrea;Mazza, Claudia
关键词：
测量日常生活中的活动能力需要处理来自多种来源的混杂因素，包括病理特征、患者特定的行走策略、环境/背景和任务目的。本研究的主要目的是提出并验证一种方案，用于模拟真实世界的步态，在一组观察中考虑所有这些因素，同时确保参与者负担和安全最小化。该方案包括八个运动任务，包括不同的速度、倾斜/台阶、表面、路径形状、认知需求，以及可能突然改变参与者行走策略的姿势。该研究从6个队列中招募了108名参与者，其中包括老年健康成年人（HA）和因帕金森病（PD）、多发性硬化症（MS）、股骨近端骨折（PFF）、慢性阻塞性肺疾病（COPD）或充血性心力衰竭（CHF）而可能改变活动能力的参与者。协议中引入的一个新颖之处是在同一任务内（例如，通过允许使用辅助设备或扶手）和跨任务增加难度的分层方法。该方案被证明是安全可行的（所有参与者都能完成，没有不良事件被记录），与标准的直线行走试验相比，增加更复杂的任务可以实现更大的步行速度。此外，它可以表示各种与日常生活相关的移动方面，因此可以用于验证现实生活中使用的监测设备。该方案允许在各种病理条件下测量步态，这表明它也可以用于检测步态的变化，例如，由于疾病的发作或进展，或由于治疗。试验注册：ISRCTN-12246987。在线版本包含补充材料，可在10.1186/s12984-022-01116-1获得。
Measuring mobility in daily life entails dealing with confounding factors arising from multiple sources, including pathological characteristics, patient specific walking strategies, environment/context, and purpose of the task. The primary aim of this study is to propose and validate a protocol for simulating real-world gait accounting for all these factors within a single set of observations, while ensuring minimisation of participant burden and safety. The protocol included eight motor tasks at varying speed, incline/steps, surface, path shape, cognitive demand, and included postures that may abruptly alter the participants’ strategy of walking. It was deployed in a convenience sample of 108 participants recruited from six cohorts that included older healthy adults (HA) and participants with potentially altered mobility due to Parkinson’s disease (PD), multiple sclerosis (MS), proximal femoral fracture (PFF), chronic obstructive pulmonary disease (COPD) or congestive heart failure (CHF). A novelty introduced in the protocol was the tiered approach to increase difficulty both within the same task (e.g., by allowing use of aids or armrests) and across tasks. The protocol proved to be safe and feasible (all participants could complete it and no adverse events were recorded) and the addition of the more complex tasks allowed a much greater spread in walking speeds to be achieved compared to standard straight walking trials. Furthermore, it allowed a representation of a variety of daily life relevant mobility aspects and can therefore be used for the validation of monitoring devices used in real life. The protocol allowed for measuring gait in a variety of pathological conditions suggests that it can also be used to detect changes in gait due to, for example, the onset or progression of a disease, or due to therapy. Trial registration: ISRCTN—12246987. The online version contains supplementary material available at 10.1186/s12984-022-01116-1.
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影响因子：
3.7
作者：
Kluge F;Del Din S;Cereatti A;Gaßner H;Hansen C;Helbostad JL;Klucken J;Küderle A;Müller A;Rochester L;Ullrich M;Eskofier BM;Mazzà C;Mobilise-D consortium
通讯作者：
Mobilise-D consortium
影响因子：
2.9
作者：
Mazzà C;Alcock L;Aminian K;Becker C;Bertuletti S;Bonci T;Brown P;Brozgol M;Buckley E;Carsin AE;Caruso M;Caulfield B;Cereatti A;Chiari L;Chynkiamis N;Ciravegna F;Del Din S;Eskofier B;Evers J;Garcia Aymerich J;Gazit E;Hansen C;Hausdorff JM;Helbostad JL;Hiden H;Hume E;Paraschiv-Ionescu A;Ireson N;Keogh A;Kirk C;Kluge F;Koch S;Küderle A;Lanfranchi V;Maetzler W;Micó-Amigo ME;Mueller A;Neatrour I;Niessen M;Palmerini L;Pluimgraaff L;Reggi L;Salis F;Schwickert L;Scott K;Sharrack B;Sillen H;Singleton D;Soltani A;Taraldsen K;Ullrich M;Van Gelder L;Vereijken B;Vogiatzis I;Warmerdam E;Yarnall A;Rochester L
通讯作者：
Rochester L
影响因子：
5.1
作者：
Shah VV;McNames J;Mancini M;Carlson-Kuhta P;Spain RI;Nutt JG;El-Gohary M;Curtze C;Horak FB
通讯作者：
Horak FB
影响因子：
5.7
作者：
Bonci, Tecla;Salis, Francesca;Scott, Kirsty;Alcock, Lisa;Becker, Clemens;Bertuletti, Stefano;Buckley, Ellen;Caruso, Marco;Cereatti, Andrea;Del Din, Silvia;Gazit, Eran;Hansen, Clint;Hausdorff, Jeffrey M.;Maetzler, Walter;Palmerini, Luca;Rochester, Lynn;Schwickert, Lars;Sharrack, Basil;Vogiatzis, Ioannis;Mazza, Claudia
通讯作者：
Mazza, Claudia
影响因子：
3.2
作者：
Lee, Jung Keun;Park, Edward J.
通讯作者：
Park, Edward J.