Exercise responses in pregnant sheep: blood gases, temperatures, and fetal cardiovascular system.

Exercise responses in pregnant sheep: blood gases, temperatures, and fetal cardiovascular system.
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怀孕羊的运动反应:血气、体温和胎儿心血管系统。

DOI:
10.1152/jappl.1983.55.3.842
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发表时间:
1983
期刊:
Journal of applied physiology: respiratory, environmental and exercise physiology
影响因子:
--
通讯作者:
Longo,LD
Longo,LD
中科院分区:
--
文献类型:
--
作者:
Lotgering,FK;Gilbert,RD;Longo,LD

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为了研究母亲运动对胎儿的影响,我们测量了母亲和胎儿的体温和血气,并计算了12只长期插管的近足月绵羊在三种不同的跑步机运动方案下的子宫耗氧量。我们还测量了胎儿儿茶酚胺浓度、心率、血压、心输出量、血流分布、血容量和胎盘弥散量。母体和胎儿体温平均最大分别升高1.5 +/- 0.5(SE)和1.3 +/- 0.1 ℃。我们校正了母体和胎儿的血气值与体内温度的关系。在70%最大O2消耗量的长时间(40分钟)运动期间,母体动脉O2分压(PO 2)接近耗竭,增加13%,最大值为116.7 +/- 4.0 Torr,而CO2分压(PCO 2)降低28%,为27.6 +/- 2.2 Torr。胎仔动脉PO 2降低11%,最小值为23.2 +/- 1.6 Torr,O2含量降低26%,最小值为4.3 +/- 0.6 ml X dl-1,PCO 2降低8%,最小值为49.6 +/- 3.2 Torr,但pH值无显著变化。恢复几乎在20分钟内完成。在运动过程中,尽管子宫血流量减少,因为血液浓缩和增加O2提取,总的子宫O2消耗量保持不变。胎儿动脉氧分压降低3 Torr和氧分压降低1.5ml × dl-1,并不引起心血管系统的重大变化或儿茶酚胺的释放。这些发现表明,母亲的运动并不代表一个主要的压力或缺氧事件的胎儿。
In an effort to examine the effects of maternal exercise on the fetus we measured maternal and fetal temperatures and blood gases and calculated uterine O2 consumption in response to three different treadmill exercise regimens in 12 chronically catheterized near-term sheep. We also measured fetal catecholamine concentrations, heart rate, blood pressure, cardiac output, blood flow distribution, blood volume, and placental diffusing capacity. Maternal and fetal temperatures increased a mean maximum of 1.5 +/- 0.5 (SE) and 1.3 +/- 0.1 degrees C, respectively. We corrected maternal and fetal blood gas values for the temperatures in vivo. Maternal arterial partial pressure of O2 (PO2), near exhaustion during prolonged (40 min) exercise at 70% maximal O2 consumption, increased 13% to a maximum of 116.7 +/- 4.0 Torr, whereas partial pressure of CO2 (PCO2) decreased by 28% to 27.6 +/- 2.2 Torr. Fetal arterial PO2 decreased 11% to a minimum of 23.2 +/- 1.6 Torr, O2 content by 26% to 4.3 +/- 0.6 ml X dl -1, PCO2 by 8% to 49.6 +/- 3.2 Torr, but pH did not change significantly. Recovery was virtually complete within 20 min. During exercise total uterine O2 consumption was maintained despite the reduction in uterine blood flow because of hemoconcentration and increased O2 extraction. The decrease of 3 Torr in fetal arterial PO2 and 1.5 ml X dl -1 in O2 content did not result in major cardiovascular changes or catecholamine release. These findings suggest that maternal exercise does not represent a major stressful or hypoxic event to the fetus.
DOI: --
发表时间: 1965
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影响因子: --
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