Whisker-mediated texture discrimination learning in freely moving mice.
Whisker-mediated texture discrimination learning in freely moving mice.
复制标题
自由移动小鼠的晶须介导的纹理辨别学习。
DOI：
10.1037/xan0000212
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Pacchiarini N
中科院分区：
文献类型：
--
作者：
Pacchiarini N
纹理常作为一种方便的刺激维度来研究啮齿动物辨别学习的各个方面。然而，纹理辨别学习的基础往往没有经过测试：尽管学习可能涉及到须系统，但它也可能基于其他感官（如嗅觉或视觉）。在这里，我们研究了小鼠是否使用它们的须系统来学习纹理识别。老鼠被放置在一个用微弱红光照亮的装置中，老鼠必须知道两个装满木屑的碗中哪一个含有埋藏的奖励。碗的外表面3d打印出不同的纹理（沟槽或光滑）。在60分钟的实验中，老鼠学会了在一个碗（如沟槽）中挖洞，而不是在另一个碗（如光滑）中挖洞，以获得奖励。这种纹理识别和气味识别被保留过夜（实验1和2）；剃须会干扰基于碗的质地的学习，但不会影响基于碗中木屑气味的学习（实验3和4）。这些结果为研究啮齿动物纹理学习的行为和大脑基础提供了可靠的基础。
Texture is often used as a convenient stimulus dimension to study aspects of discrimination learning in rodents. However, the basis of texture discrimination learning is often left untested: Although learning could involve the whisker system, it could also be based on other senses (eg, olfactory or visual). Here, we investigated whether mice use their whisker system to learn texture discriminations. Mice were placed in an apparatus illuminated with a dim red light, and the mice had to learn which of 2 sawdust-filled bowls contained a buried reward. The outer surfaces of the bowls were 3− D printed with different textures (grooved or smooth). Within a 60-min session, mice learned to dig in 1 bowl (eg, grooved) rather than the other (eg, smooth) to gain the reward. This texture discrimination and an equivalent odor discrimination were retained overnight (Experiments 1 and 2); and whisker trimming disrupted learning based on the texture of the bowls but not learning based on the odor of the sawdust in the bowls (Experiments 3 and 4). These results provide a secure basis upon which to investigate the behavioral and brain basis of texture learning in rodents.
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影响因子：
3.3
作者：
Stuettgen, Maik C.;Schwarz, Cornelius
通讯作者：
Schwarz, Cornelius
影响因子：
2.9
作者：
L. Botly;E. Rosa
通讯作者：
E. Rosa
影响因子：
3
作者：
Davies DA;Greba Q;Howland JG
通讯作者：
Howland JG
大鼠触觉刺激的知觉学习：维度处理的变化
DOI：
--
发表时间：
2016
期刊：
Journal of Experimental Psychology: Animal Learning and Cognition
影响因子：
--
作者：
Luke M. Montuori;R. C. Honey
通讯作者：
R. C. Honey
影响因子：
2.5
作者：
Knutsen, PM;Derdikman, D;Ahissar, E
通讯作者：
Ahissar, E