Enterovirus A71 Proteins: Structure and Function.
Enterovirus A71 Proteins: Structure and Function.
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肠道病毒 A71 蛋白:结构和功能
DOI:
10.3389/fmicb.2018.00286
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发表时间:
2018
影响因子:
5.2
通讯作者:
Mao L
中科院分区:
文献类型:
--
作者:
Yuan J;Shen L;Wu J;Zou X;Gu J;Chen J;Mao L
Enterovirus A71 (EV-A71) infection has grown to become a serious threat to global public health. It is one of the major causes of hand, foot, and mouth disease (HFMD) in infants and young children. EV-A71 can also infect the central nervous system (CNS) and induce diverse neurological complications, such as brainstem encephalitis, aseptic meningitis, and acute flaccid paralysis, or even death. Viral proteins play a crucial role in EV-A71 infection. Many recent studies have discussed the structure and function of EV-A71 proteins, and the findings reported will definitely aid the development of vaccines and therapeutic approaches. This article reviews the progress in the research on the structure and function of EV-A71 proteins. Available literature can provide a basis for studying the pathogenesis of EV-A71 infection in detail.
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