Parental Vaccine Hesitancy and Association With Childhood Diphtheria, Tetanus Toxoid, and Acellular Pertussis; Measles, Mumps, and Rubella; Rotavirus; and Combined 7-Series Vaccination.
Parental Vaccine Hesitancy and Association With Childhood Diphtheria, Tetanus Toxoid, and Acellular Pertussis; Measles, Mumps, and Rubella; Rotavirus; and Combined 7-Series Vaccination.
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DOI：
10.1016/j.amepre.2021.08.015
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发表时间：
2022-03
影响因子：
5.5
通讯作者：
Singleton JA
中科院分区：
文献类型：
--
作者：
Nguyen KH;Srivastav A;Lindley MC;Fisher A;Kim D;Greby SM;Lee J;Singleton JA
父母对接种疫苗的犹豫可能是常规儿童免疫接种的障碍，并增加了接种疫苗可预防疾病的风险。这项研究探讨了父母对疫苗接种率的犹豫的影响。本研究评估了父母疫苗犹豫与儿童疫苗接种覆盖率的关系，包括≥4剂白喉、破伤风类毒素和无细胞百日咳疫苗; ≥1剂麻疹、腮腺炎和风疹疫苗;最新轮状病毒疫苗;使用2018年和2019年全国免疫调查-儿童的数据，对19-35个月的儿童样本进行了7个疫苗系列的合并覆盖率（N= 7，645）。在疫苗接种犹豫和非犹豫的父母之间，以及在疫苗接种不足时犹豫的人群归因风险分数（定义为每种疫苗都不是最新的），估计了疫苗接种覆盖率多变量分析的调整差异。近四分之一的父母报告说对疫苗犹豫不决，其中非西班牙裔黑人（37.0%）或西班牙裔（30.1%）儿童的父母，高中或以下教育程度的母亲（31.9%）和生活在贫困线以下的家庭（35.6%）的疫苗犹豫比例最高。犹豫不决的父母的儿童所有疫苗的接种覆盖率低于非犹豫不决的父母的儿童，接种不足犹豫不决的人群比例范围为15%至25%，≥1剂麻疹，腮腺炎和风疹疫苗的比例最高。在19 - 35个月的儿童中，父母对疫苗接种的犹豫可能导致高达25%的疫苗接种不足。需要实施解决父母疫苗犹豫的战略，以提高儿童疫苗接种覆盖率，并尽量减少他们患疫苗可预防疾病的风险。
Parental vaccine hesitancy can be a barrier to routine childhood immunization and contribute to greater risk for vaccine-preventable diseases. This study examines the impact of parental vaccine hesitancy on childhood vaccination rates. This study assessed the association of parental vaccine hesitancy on child vaccination coverage with ≥4 doses of diphtheria, tetanus toxoid, and acellular pertussis vaccine; ≥1 dose of measles, mumps, and rubella vaccine; up-to-date rotavirus vaccine; and combined 7-vaccine series coverage for a sample of children aged 19–35 months using data from the 2018 and 2019 National Immunization Survey-Child (N=7,645). Adjusted differences in multivariable analyses of vaccination coverage were estimated among vaccine hesitant and nonhesitant parents and population attributable risk fraction of hesitancy on undervaccination, defined as not being up to date for each vaccine. Almost a quarter of parents reported being vaccine hesitant, with the highest proportion of vaccine hesitancy among parents of children who are non-Hispanic Black (37.0%) or Hispanic (30.1%), mothers with a high school education or less (31.9%), and households living below the poverty level (35.6%). Childhood vaccination coverage for all vaccines was lower for children of hesitant than nonhesitant parents, and the population attributable fraction of hesitancy on undervaccination ranged from 15% to 25%, with the highest percentage for ≥1 dose of measles, mumps, and rubella vaccine. Parental vaccine hesitancy may contribute up to 25% of undervaccination among children aged 19−35 months. Implementation of strategies to address parental vaccine hesitancy is needed to improve vaccination coverage for children and minimize their risk of vaccine-preventable diseases.
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影响因子：
9.7
作者：
Kennedy, Allison;LaVail, Katherine;Landry, Sarah
通讯作者：
Landry, Sarah
影响因子：
25.4
作者：
Brewer, Noel T.;Chapman, Gretchen B.;Kempe, Allison
通讯作者：
Kempe, Allison
DOI：
10.15585/mmwr.mm6942a1
发表时间：
2020-10-23
期刊：
MMWR. Morbidity and mortality weekly report
影响因子：
--
作者：
Hill HA;Yankey D;Elam-Evans LD;Singleton JA;Pingali SC;Santibanez TA
通讯作者：
Santibanez TA
影响因子：
5.1
作者：
Nadeau, Jessica A.;Bednarczyk, Robert A.;McNutt, Louise-Anne
通讯作者：
McNutt, Louise-Anne
影响因子：
33.9
作者：
Robinson, Candice L.;Bernstein, Henry;Szilagyi, Peter
通讯作者：
Szilagyi, Peter