Chromosomal Analysis in Crotophaga ani (Aves, Cuculiformes) Reveals Extensive Genomic Reorganization and an Unusual Z-Autosome Robertsonian Translocation.
Chromosomal Analysis in Crotophaga ani (Aves, Cuculiformes) Reveals Extensive Genomic Reorganization and an Unusual Z-Autosome Robertsonian Translocation.
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染色体分析揭示了广泛的基因组重组和一种不寻常的常染色体罗伯逊易位。
DOI：
10.3390/cells10010004
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发表时间：
2020-12-22
期刊：
影响因子：
6
通讯作者：
Griffin DK
中科院分区：
文献类型：
--
作者：
Kretschmer R;Gunski RJ;Garnero ADV;de Freitas TRO;Toma GA;Cioffi MB;Oliveira EHC;O'Connor RE;Griffin DK
虽然杜鹃(Aves，Cuculiformes)的细胞遗传学研究显示了一种有趣的核型变异，如染色体形态和二倍体数量的变异，但它们的染色体组织和进化以及与其他鸟类的关系尚不清楚。因此，我们结合传统的细胞遗传学方法和分子细胞遗传学方法来研究鸡和光嘴鸟(Crotophaga Ani)之间的染色体同源性。我们的研究结果表明，在华支睾吸虫中存在广泛的染色体重组，染色体间的重排涉及到大染色体和微染色体。在包括Z染色体在内的一些大染色体上观察到染色体内重排。进化上最值得注意的发现是罗伯逊式的17号微染色体和Z染色体之间的易位，这在鸟类中是罕见的。此外，这里测试的简单短重复序列(SSR)优先聚集在微染色体以及Z和W染色体中，除了W染色体外，与构成异染色质的区域没有关系。综上所述，我们的结果表明，鸟类的性染色体比先前假设的要复杂得多，并揭示了微染色体在鸟类性染色体进化中的作用，尤其是杜鹃。
Although cytogenetics studies in cuckoos (Aves, Cuculiformes) have demonstrated an interesting karyotype variation, such as variations in the chromosome morphology and diploid number, their chromosome organization and evolution, and relation with other birds are poorly understood. Hence, we combined conventional and molecular cytogenetic approaches to investigate chromosome homologies between chicken and the smooth-billed ani (Crotophaga ani). Our results demonstrate extensive chromosome reorganization in C. ani, with interchromosomal rearrangements involving macro and microchromosomes. Intrachromosomal rearrangements were observed in some macrochromosomes, including the Z chromosome. The most evolutionary notable finding was a Robertsonian translocation between the microchromosome 17 and the Z chromosome, a rare event in birds. Additionally, the simple short repeats (SSRs) tested here were preferentially accumulated in the microchromosomes and in the Z and W chromosomes, showing no relationship with the constitutive heterochromatin regions, except in the W chromosome. Taken together, our results suggest that the avian sex chromosome is more complex than previously postulated and revealed the role of microchromosomes in the avian sex chromosome evolution, especially cuckoos.
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影响因子：
1.6
作者：
Dobigny, G;Ozouf-Costaz, C;Volobouev, V
通讯作者：
Volobouev, V
影响因子：
3.7
作者：
dos Santos, Michelly da Silva;Kretschmer, Rafael;Correa de Oliveira, Edivaldo Herculano
通讯作者：
Correa de Oliveira, Edivaldo Herculano
影响因子：
1.7
作者：
Griffin, D. K.;Robertson, L. B. W.;Skinner, B. M.
通讯作者：
Skinner, B. M.
影响因子：
2.4
作者：
Joseph, Sunitha;O'Connor, Rebecca E.;Griffin, Darren K.
通讯作者：
Griffin, Darren K.
影响因子：
1.7
作者：
Cioffi, M. B.;Martins, C.;Bertollo, L. A. C.
通讯作者：
Bertollo, L. A. C.