Strong selection genome-wide enhances fitness trade-offs across environments and episodes of selection.
Strong selection genome-wide enhances fitness trade-offs across environments and episodes of selection.
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DOI：
10.1111/evo.12259
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发表时间：
2014-01
期刊：
影响因子：
--
通讯作者：
Mitchell-Olds T
中科院分区：
文献类型：
--
作者：
Anderson JT;Lee CR;Mitchell-Olds T
在选择和环境的事件健身权衡影响生活史进化和适应性种群分化。记录这些权衡仍然具有挑战性，因为选择可以在时间和空间的大小和方向上变化。在这里，我们评估健身权衡的水平，整个生物体和数量性状位点（QTL）在多年的实地研究Boechera stricta（油菜科），一种遗传上易于处理的芥末原产于落基山脉。互惠本地适应明显的生存能力，但不是生殖健康的组成部分。相反，本地基因组只有在高纬度花园中才具有繁殖力优势。通过估计实现选择系数从个体水平上的生存能力和繁殖成功的数据和置换的数据来推断的意义，我们研究了遗传基础的健身权衡。这种分析方法（条件中性-拮抗多效性，CNAP）确定了开花物候QTL（适应成本）的遗传权衡，并揭示了整个健身组件（繁殖成本）的遗传权衡。这些模式不会出现在传统的基于方差分析的QTL定位。我们的分析框架可以应用到其他系统，调查健身权衡。这项任务变得越来越重要，因为气候变化可能会改变健身景观，可能会破坏经过几代人进化的健身权衡。
Fitness tradeoffs across episodes of selection and environments influence life history evolution and adaptive population divergence. Documenting these tradeoffs remains challenging as selection can vary in magnitude and direction through time and space. Here, we evaluate fitness tradeoffs at the levels of the whole organism and the quantitative trait locus (QTL) in a multiyear field study of Boechera stricta (Brassicaceae), a genetically tractable mustard native to the Rocky Mountains. Reciprocal local adaptation was pronounced for viability, but not for reproductive components of fitness. Instead, local genomes had a fecundity advantage only in the high latitude garden. By estimating realized selection coefficients from individual level data on viability and reproductive success and permuting the data to infer significance, we examined the genetic basis of fitness tradeoffs. This analytical approach (Conditional Neutrality-Antagonistic Pleiotropy, CNAP) identified genetic tradeoffs at a flowering phenology QTL (costs of adaptation) and revealed genetic tradeoffs across fitness components (costs of reproduction). These patterns would not have emerged from traditional ANOVA-based QTL mapping. Our analytical framework can be applied to other systems to investigate fitness tradeoffs. This task is becoming increasingly important as climate change may alter fitness landscapes, potentially disrupting fitness tradeoffs that took many generations to evolve.
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DOI：
10.1111/j.1558-5646.2010.01175.x
发表时间：
2011-03
期刊：
Evolution; international journal of organic evolution
影响因子：
--
作者：
Anderson JT;Lee CR;Mitchell-Olds T
通讯作者：
Mitchell-Olds T
影响因子：
5.5
作者：
Gonzalo-Turpin, Heloise;Hazard, Laurent
通讯作者：
Hazard, Laurent
影响因子：
3.3
作者：
Anderson, Jill T.;Geber, Monica A.
通讯作者：
Geber, Monica A.
影响因子：
56.9
作者：
Fournier-Level, A.;Korte, A.;Wilczek, A. M.
通讯作者：
Wilczek, A. M.
影响因子：
5.5
作者：
Bennington, Cynthia C.;Fetcher, Ned;McGraw, James B.
通讯作者：
McGraw, James B.