Estimating the prevalence and awareness rates of hypertension in Africa: a systematic analysis.

Estimating the prevalence and awareness rates of hypertension in Africa: a systematic analysis.
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DOI:
10.1371/journal.pone.0104300
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发表时间:
2014
期刊:
影响因子:
3.7
通讯作者:
Basquill C
Basquill C
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Adeloye D;Basquill C

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非洲的高血压负担很高,而且由于人口快速增长和老龄化,非洲大陆的确切负担仍远未可知。我们的目的是根据“≥140/90 mm Hg”的界限来估计非洲高血压的患病率和知晓率。我们对 Medline、EMBASE 和 Global Health 进行了系统检索。检索日期设定为 1980 年 1 月至 2013 年 12 月。我们纳入了基于人群的高血压研究,这些研究在 15 岁以上的人群中进行,并提供了非洲高血压患病率的数值估计。非洲混合、农村和城市环境中高血压的总体汇总患病率是根据报告的粗患病率估计的。采用元回归流行病学模型,利用 1990 年、2000 年、2010 年和 2030 年的联合国人口统计数据,分别确定这四年非洲的高血压患病率和病例数。我们的检索返回了 7680 篇出版物,其中 92 篇符合选择标准。 1990年,非洲高血压的总体患病率为19.7%,2000年为27.4%,2010年为30.8%,汇总知晓率(以高血压病例百分比表示)分别为16.9%、29.2%和33.7%。根据模型,1990年估计有超过5460万例高血压病例,2000年有9230万例,2010年有1.302亿例,预计到2030年将增加到2.168亿例;各年龄调整患病率分别为 19.1% (13.9, 25.5)、24.3% (23.3, 31.6)、25.9% (23.5, 34.0) 和 25.3% (24.3, 39.7)。我们的研究结果表明,非洲高血压患病率正在增加,但许多高血压患者并不了解自己的病情。我们希望这项研究能够促进适当的政策反应,以提高非洲高血压的认识、控制和整体管理。
The burden of hypertension is high in Africa, and due to rapid population growth and ageing, the exact burden on the continent is still far from being known. We aimed to estimate the prevalence and awareness rates of hypertension in Africa based on the cut off “≥140/90 mm Hg”. We conducted a systematic search of Medline, EMBASE and Global Health. Search date was set from January 1980 to December 2013. We included population-based studies on hypertension, conducted among people aged ≥15 years and providing numerical estimates on the prevalence of hypertension in Africa. Overall pooled prevalence of hypertension in mixed, rural and urban settings in Africa were estimated from reported crude prevalence rates. A meta-regression epidemiological modelling, using United Nations population demographics for the years 1990, 2000, 2010 and 2030, was applied to determine the prevalence rates and number of cases of hypertension in Africa separately for these four years. Our search returned 7680 publications, 92 of which met the selection criteria. The overall pooled prevalence of hypertension in Africa was 19.7% in 1990, 27.4% in 2000 and 30.8% in 2010, each with a pooled awareness rate (expressed as percentage of hypertensive cases) of 16.9%, 29.2% and 33.7%, respectively. From the modelling, over 54.6 million cases of hypertension were estimated in 1990, 92.3 million cases in 2000, 130.2 million cases in 2010, and a projected increase to 216.8 million cases of hypertension by 2030; each with an age-adjusted prevalence of 19.1% (13.9, 25.5), 24.3% (23.3, 31.6), 25.9% (23.5, 34.0), and 25.3% (24.3, 39.7), respectively. Our findings suggest the prevalence of hypertension is increasing in Africa, and many hypertensive individuals are not aware of their condition. We hope this research will prompt appropriate policy response towards improving the awareness, control and overall management of hypertension in Africa.
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