Repeated Inhalation of Peppermint Essential Oil Improves Exercise Performance in Endurance-Trained Rats.

Repeated Inhalation of Peppermint Essential Oil Improves Exercise Performance in Endurance-Trained Rats.
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DOI:
10.3390/nu15112480
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发表时间:
2023-05-26
期刊:
影响因子:
5.9
通讯作者:
Gao F
Gao F
中科院分区:
医学2区
文献类型:
--
作者:
Zhang W;Shi R;Gao T;Hu Y;Zhou J;Li C;Wang P;Yang H;Xing W;Dong L;Gao F

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薄荷精油天然安全,具有抗氧化和抗炎作用,在缓解疲劳和提高运动能力方面一直是研究热点。然而,相关的研究报告有争议的结果,其机制仍不清楚。在这里,我们发现吸入薄荷精油可以显着延长接受2周负重游泳训练的大鼠的疲惫时间。对Sprague-Dawley大鼠进行2周的负重强迫游泳方案。在每次游泳之前,通过吸入给予大鼠薄荷精油。在方案结束时进行力竭游泳试验。与没有精油治疗的运动大鼠相比,用精油治疗的大鼠的力竭时间显著延长。此外,经治疗的大鼠还表现出减少由耐力运动引起的氧化损伤。值得注意的是,接受两周精油吸入而不进行游泳训练的大鼠没有显示出改善的运动表现。研究结果表明,反复吸入薄荷精油可以增强耐力训练的效果,并部分通过防止氧化损伤来改善运动表现。
Peppermint essential oil, being natural and safe, with antioxidant and anti-inflammatory properties, has long been a research interest in relieving fatigue and improving exercise performance. However, the related studies report controversial results, and the mechanisms remain unclear. Here we found that inhalation of peppermint essential oil significantly extended the exhaustion time in rats subjected to 2-week weight-bearing swimming training. Sprague-Dawley rats were subjected to a 2-week weight-loaded forced swimming regimen. Prior to each swimming session, the rats were administered peppermint essential oil via inhalation. An exhaustive swimming test was performed at the end of the protocol. Rats treated with essential oil had significantly extended time to exhaustion compared with exercised rats without essential oil treatment. In addition, treated rats also showed reduced oxidative damage induced by endurance exercise. Notably, the rats receiving two-week essential oil inhalation while not subjected to swimming training did not show improved exercise performance. The findings demonstrate that repeated inhalation of peppermint essential oil enhances the effects of endurance training and improves exercise performance partially by preventing oxidative damage.
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