Effect of green tea and Tai Chi on bone health in postmenopausal osteopenic women: a 6-month randomized placebo-controlled trial.
Effect of green tea and Tai Chi on bone health in postmenopausal osteopenic women: a 6-month randomized placebo-controlled trial.
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DOI：
10.1007/s00198-011-1731-x
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发表时间：
2012-05
影响因子：
4
通讯作者：
Wang, J-S.
中科院分区：
文献类型：
--
作者：
Shen, C-L.;Chyu, M-C.;Yeh, J. K.;Zhang, Y.;Pence, B. C.;Felton, C. K.;Brismee, J-M.;Arjmandi, B. H.;Doctolero, S.;Wang, J-S.
关键词：
绝经后骨量减少的妇女接受绿茶多酚(GTP)补充和/或太极锻炼6个月。测量骨转换生物标志物、钙代谢和肌肉力量。这项研究表明，补充GTP和太极锻炼增加了骨形成生物标志物，提高了骨转换率。太极拳运动可提高血清甲状旁腺激素水平。补充GTP、太极运动以及两者的结合都能改善绝经后骨质疏松症女性的肌肉力量。本研究评价了补充GTP和太极运动对绝经后骨质疏松症妇女血清骨转换指标(骨特异性碱性磷酸酶和抗酒石酸酸性磷酸酶，TRAP)、钙代谢和肌肉力量的影响。171名绝经后骨质疏松症妇女随机分为4组：(1)安慰剂组(每天500 mg淀粉)，(2)GTP(每天500 mg GTP)，(3)安慰剂+TC(安慰剂+TC训练，每次60分钟，每周3次)，(4)GTP+TC(GTP+TC训练)。在基线、1个月、3个月和6个月收集过夜的空腹血液和尿样进行生物标志物分析。在基线、3个月和6个月时评估肌力。150名受试者完成了为期6个月的研究。由于摄入GTP(在1个月时)和TC(在3个月时)，BAP水平显著增加。GTP(3个月时)和TC(6个月时)引起的BAP/TRAP比值变化也显著增加。TC对血清甲状旁腺激素水平升高在1个月和3个月时有显著的主效应。在6个月时，由于GTP、TC和GTP+TC干预，肌肉力量显著改善。GTP和TC均不影响血清TRAP、血、尿钙和无机磷。总之，补充GTP和TC运动增加了BAP，改善了BAP/TRAP比率。TC运动使血清甲状旁腺激素水平升高。补充GTP、TC运动以及两者的结合都能改善绝经后骨质疏松症女性的肌肉力量。
Postmenopausal women with osteopenia received green tea polyphenols (GTP) supplement and/or Tai Chi exercise for 6 months. Bone turnover biomarkers, calcium metabolism, and muscle strength were measured. This study showed that GTP supplementation and Tai Chi exercise increased bone formation biomarkers and improved bone turnover rate. Tai Chi exercise increased serum parathyroid hormone. GTP supplementation, Tai Chi exercise, and the combination of the two all improved muscle strength in postmenopausal women with osteopenia. This study evaluated the effect of GTP supplementation and Tai Chi (TC) exercise on serum markers of bone turnover (bone-specific alkaline phosphatase, BAP, and tartrate-resistant acid phosphatase, TRAP), calcium metabolism, and muscle strength in postmenopausal osteopenic women. One hundred and seventy-one postmenopausal osteopenic women were randomly assigned to four groups: (1) placebo (500 mg starch/day), (2) GTP (500 mg GTP/day), (3) placebo + TC (placebo plus TC training at 60 min/session, three sessions/week), and (4) GTP + TC (GTP plus TC training). Overnight fasting blood and urine samples were collected at baseline, 1, 3, and 6 months for biomarker analyses. Muscle strength was evaluated at baseline, 3, and 6 months. One hundred and fifty subjects completed the 6-month study. Significant increases in BAP level due to GTP intake (at 1 month) and TC (at 3 months) were observed. Significant increases in the change of BAP/TRAP ratio due to GTP (at 3 months) and TC (at 6 months) were also observed. Significant main effect of TC on the elevation in serum parathyroid hormone level was observed at 1 and 3 months. At 6 months, muscle strength significantly improved due to GTP, TC, and GTP + TC interventions. Neither GTP nor TC affected serum TRAP, serum and urinary calcium, and inorganic phosphate. In summary, GTP supplementation and TC exercise increased BAP and improved BAP/TRAP ratio. TC exercise increased serum parathyroid hormone. GTP supplementation, TC exercise, and the combination of the two all improved muscle strength in postmenopausal women with osteopenia.
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影响因子：
6.1
作者：
Ayotte, Norman W.;Stetts, Deborah M.;Greenway, Elizabeth H.
通讯作者：
Greenway, Elizabeth H.
影响因子：
7.1
作者：
Devine, Amanda;Hodgson, Jonathan M.;Prince, Richard L.
通讯作者：
Prince, Richard L.
影响因子：
4
作者：
Genaro, Patricia S.;Pereira, Giselle A. P.;Martini, Ligia A.
通讯作者：
Martini, Ligia A.
影响因子：
6.2
作者：
Halleen, JM;Alatalo, SL;Väänänen, HK
通讯作者：
Väänänen, HK
影响因子：
6.2
作者：
Jilka, Robert L.;O'Brien, Charles A.;Bartell, Shoshana M.;Weinstein, Robert S.;Manolagas, Stavros C.
通讯作者：
Manolagas, Stavros C.