Learning Recruits Neurons Representing Previously Established Associations in the Corvid Endbrain
Learning Recruits Neurons Representing Previously Established Associations in the Corvid Endbrain
复制标题
学习招募代表先前在鸦科动物端脑中建立的关联的神经元
DOI：
10.1162/jocn_a_01152
复制
发表时间：
2017
影响因子：
3.2
通讯作者：
Nieder
中科院分区：
文献类型：
--
作者：
Pidpruzhnykova;Nieder
乌鸦很快就学会了任意联想。作为这一行为的神经元相关者，在联想学习过程中，Corvid End Brain Area nidopallium caudolaterale(NCL)中的单个神经元改变了它们的反应特性。在执行延迟联想任务的乌鸦身上，他们需要将熟悉的和新奇的样本图片映射到相同的两个选择图片上，NCL神经元建立了一个共同的、预期的联想代码。在这里，我们报告了学习过程中神经元调谐的变化并不均匀地分布在记录的NCL神经元群体中。相反，这种与学习相关的变化几乎完全依赖于已经在编码熟悉的联系的神经元。只有在这样的神经元中，在学习新联想的过程中行为的改善才与学习过程中越来越多的选择性相一致。熟悉的联想和新学习的联想的选择性的大小和方向高度相关。这些对新缔合的选择性的增加只发生在延迟期的后期。此外，NCL神经元根据试验结束时的反馈信号区分正确和错误的试验结果，特别是在新学习的联系中。我们的结果表明，在联想学习过程中，任务相关的变化不是分布在Corvid NCL神经元群体中，而是局限于特定的联想选择神经元组。这种位于多通道认知整合区域NCL的联结神经元可能在乌鸦高度灵活的行为过程中发挥重要作用。
Crows quickly learn arbitrary associations. As a neuronal correlate of this behavior, single neurons in the corvid endbrain area nidopallium caudolaterale (NCL) change their response properties during association learning. In crows performing a delayed association task that required them to map both familiar and novel sample pictures to the same two choice pictures, NCL neurons established a common, prospective code for associations. Here, we report that neuronal tuning changes during learning were not distributed equally in the recorded population of NCL neurons. Instead, such learning-related changes relied almost exclusively on neurons which were already encoding familiar associations. Only in such neurons did behavioral improvements during learning of novel associations coincide with increasing selectivity over the learning process. The size and direction of selectivity for familiar and newly learned associations were highly correlated. These increases in selectivity for novel associations occurred only late in the delay period. Moreover, NCL neurons discriminated correct from erroneous trial outcome based on feedback signals at the end of the trial, particularly in newly learned associations. Our results indicate that task-relevant changes during association learning are not distributed within the population of corvid NCL neurons but rather are restricted to a specific group of association-selective neurons. Such association neurons in the multimodal cognitive integration area NCL likely play an important role during highly flexible behavior in corvids.
登录
查看更多内容
影响因子：
2.5
作者：
Anne C. Smith;S. Wirth;W. Suzuki;E. Brown
通讯作者：
Anne C. Smith;S. Wirth;W. Suzuki;E. Brown
影响因子：
16.6
作者：
Lena Veit;A. Nieder
通讯作者：
Lena Veit;A. Nieder
影响因子：
2.5
作者：
CHEN, LL;WISE, SP
通讯作者：
WISE, SP
影响因子：
2.7
作者：
Moll, Felix W.;Nieder, Andreas
通讯作者：
Nieder, Andreas
影响因子：
2.5
作者：
Freedman, DJ;Riesenhuber, M;Miller, EK
通讯作者：
Miller, EK