The Role of Emergence in Genetically Informed Relationships Research: A Methodological Analysis.
The Role of Emergence in Genetically Informed Relationships Research: A Methodological Analysis.
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DOI：
10.1007/s10519-018-9934-y
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发表时间：
2019-03
影响因子：
2.6
通讯作者：
Kendler KS
中科院分区：
文献类型：
--
作者：
Salvatore JE;Kendler KS
这篇论文提供了一个关于关系的遗传学研究的批判性分析，重点是不相关个体（如配偶）之间的关系。迄今为止，该领域的研究使用传统的行为遗传学框架将关系相关结果的差异划分为遗传和环境成分，或检查关系因素与其他结果之间的基因-环境相互作用。然而，这种传统的方法与关系科学领域长期以来的理解是不一致的，即在预测共同的结果时，伴侣双方的特征很重要，也就是说，结果是突然出现的。我们简要地考察了涌现的哲学概念，并讨论了在遗传知情关系研究中建立二元结果模型的方法。我们还回顾了社会遗传效应的相关主题，这是指社会伴侣的基因型对先证者表型的影响。遗传信息的二元视角对我们理解从基因型→共享或个体水平表型的途径具有潜在的重要影响，并更充分地认识到遗传和社会/环境因素如何共同影响人类行为的复杂性。
This paper provides a critical analysis of genetically informed research on relationships, with an emphasis on relationships among unrelated individuals (e.g., spouses). To date, research in this area has used traditional behavioral genetic frameworks to either partition the variance in relationship-related outcomes into genetic and environmental components, or to examine gene-environment interplay between relationship factors and other outcomes. However, this conventional approach is at odds with the long-standing understanding from the field of relationship science that both partners’ characteristics matter when predicting shared outcomes—that is, outcomes that are emergent. We examine briefly the philosophical concept of emergence, and discuss ways to model dyadic outcomes in genetically informed relationships research. We also review the related topic of social genetic effects, which refer to the influence of a social partner’s genotype on a proband’s phenotype. A genetically informed dyadic perspective has potentially important consequences for our understanding of the pathways from genotype→shared or individual-level phenotypes, and more fully recognizes the complexity of how genetic and social/environmental factors come together to influence human behavior.
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影响因子：
2.6
作者：
Eaves, Lindon J.;St Pourcain, Beate;Smith, George Davey;York, Timothy P.;Evans, David M.
通讯作者：
Evans, David M.
影响因子：
2.1
作者：
Dudbridge F
通讯作者：
Dudbridge F
DOI：
10.1146/annurev-clinpsy-050817-084847
发表时间：
2018-05-07
影响因子：
18.4
作者：
Bogdan R;Baranger DAA;Agrawal A
通讯作者：
Agrawal A
DOI：
10.1073/pnas.1711803115
发表时间：
2018-01-23
影响因子：
11.1
作者：
Domingue, Benjamin W.;Belsky, Daniel W.;Harris, Kathleen Mullan
通讯作者：
Harris, Kathleen Mullan
影响因子：
6
作者：
D'Onofrio, Brian M.;Turkheimer, Eric;Martin, Nicholas G.
通讯作者：
Martin, Nicholas G.