Ovarian metabolism of xenobiotics.
Ovarian metabolism of xenobiotics.
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DOI：
10.1258/ebm.2011.011051
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发表时间：
2011-07
期刊：
影响因子：
--
通讯作者：
Keating AF
中科院分区：
文献类型：
--
作者：
Bhattacharya P;Keating AF
At birth, the mammalian ovary contains a finite number of primordial follicles, which once depleted, cannot be replaced. Xenobiotic exposures can destroy primordial follicles resulting in premature ovarian failure and, consequently, early entry into menopause. A number of chemical classes can induce premature ovarian failure, including environmental, chemotherapeutic and industrial exposures. While our knowledge on the mechanistic events that occur in the ovary with chemical exposures is increasing, our understanding of the ovary's capacity to metabolize such compounds is less established. This review will focus on three chemicals for which information on ovarian metabolism is known: trichloroethylene, 7,12-dimethylbenz[a]anthracene and 4-vinylcyclohexene. The current state of understanding of ovarian bioactivation and detoxification processes for each will be described.
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影响因子：
56.9
作者：
BENGTSSON, M;RYDSTROM, J
通讯作者：
RYDSTROM, J
DOI：
10.1002/mrd.1120140310
发表时间：
1986-01-01
期刊：
GAMETE RESEARCH
影响因子：
--
作者：
CALVIN, HI;GROSSHANS, K;BLAKE, EJ
通讯作者：
BLAKE, EJ
影响因子：
4.8
作者：
Hattori, N;Fujiwara, H;Ueda, M
通讯作者：
Ueda, M
影响因子：
3.3
作者：
HOOSER, SB;DOUDS, DP;SIPES, IG
通讯作者：
SIPES, IG
影响因子：
4.5
作者：
Brink, Thore C.;Demetrius, Lloyd;Lehrach, Hans;Adjaye, James
通讯作者：
Adjaye, James