Schizosaccharomyces versatilis represents a distinct evolutionary lineage

Schizosaccharomyces versatilis represents a distinct evolutionary lineage
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多功能裂殖酵母代表了独特的进化谱系

DOI:
10.1101/2023.09.04.556188
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发表时间:
2023
期刊:
--
影响因子:
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通讯作者:
Etherington G
Etherington G
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作者:
Etherington G

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日本裂殖酵母(Schizosophylomycesjaponicus)目前分为两个变种--S. japonicusvar.japonicusandS. japonicusvar.versatilis.在这里,我们检查变种。acetitilisisolate CBS 5679。CBS 5679基因组与S. japonicusvar. japonicus在编码序列水平上的同源性最高,系统发育分析表明该基因已从日本血吸虫中分离出来。japonicuslineage 25 million百万years年份ago. CBS 5679基因组包含1号和2号染色体之间的相互易位,以及几个大的倒位。与主要易位相关的基因的产物与“代谢”和“细胞组装”本体论术语相关。我们进一步表明,CBS 5679不产生可行的后代与参考菌株的S。- 是的虽然CBS 5679与S. patientis相比,与var. artitilisas的“模式”菌株具有更接近的相似性,但它与模式菌株不相同,表明var. artitilisis内的种群结构。我们建议,S.本文介绍了日本裂殖酵母的分类地位。从S. japonicusaround 25 million百万years年份ago前.在与S.日本血吸虫染色体易位是1号和2号染色体之间的相互易位。基因本体论中关于易位基因的术语富含与“代谢”和“细胞组装”相关的术语。
The fission yeast speciesSchizosaccharomyces japonicusis currently divided into two varieties –S. japonicusvar.japonicusandS. japonicusvar.versatilis. Here we examine the var.versatilisisolate CBS5679. The CBS5679 genome shows 88% coding sequence identity to the reference genome ofS. japonicusvar.japonicusat the coding sequence level, with phylogenetic analyses suggesting that it has split from theS. japonicuslineage 25 million years ago. The CBS5679 genome contains a reciprocal translocation between chromosomes 1 and 2, together with several large inversions. The products of genes linked to the major translocation are associated with “metabolism” and “cellular assembly” ontology terms. We further show that CBS5679 does not generate viable progeny with the reference strain ofS. japonicus. Although CBS5679 shares closer similarity to the “type” strain of var.versatilisas compared to S.japonicus, it is not identical to the type strain, suggesting population structure within var.versatilis. We recommend that the taxonomic status ofS. japonicusvar.versatilisis raised, with it being treated as a separate species,Schizosaccharomyces versatilis.Take-awayThe taxonomic status ofSchizosaccharomyces versatilisis addressed.S. versatilisdiverged fromS. japonicusaround 25 million years ago.S. versatilisdoes not produce viable progeny in crosses withS. japonicus.S. versatilishas a reciprocal translocation between chromosomes 1 and 2.The Gene Ontology terms for genes in the translocations are enriched for terms connected to “metabolism” and “cellular assembly”.
裂殖酵母 Lindner 属内杂交和原生质体融合的杂交研究
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