Neural correlates of true memory, false memory, and deception.
Neural correlates of true memory, false memory, and deception.
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DOI：
10.1093/cercor/bhn037
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发表时间：
2008-12
期刊：
影响因子：
--
通讯作者：
Fujii T
中科院分区：
文献类型：
--
作者：
Abe N;Okuda J;Suzuki M;Sasaki H;Matsuda T;Mori E;Tsukada M;Fujii T
我们使用功能性磁共振成像（fMRI）来确定神经活动是否可以区分真实记忆，错误记忆和欺骗。受试者听到一系列语义相关的单词，然后被要求对旧单词、语义相关的非研究单词（错误识别的诱饵）和无关的新单词进行识别判断。他们还被要求对一半的旧词和不相关的新词做出欺骗性的反应。有3个主要发现。首先，与执行功能支持欺骗的概念一致，两种类型的欺骗（假装知道和假装不知道）招募了前额叶活动。第二，与感觉再激活假说相一致，真识别和假识别之间的差异被发现在左颞顶区，可能参与编码错误呈现的单词。第三，左侧前额叶皮层在相对于正确拒绝和错误识别的假装知道过程中被激活，而右侧前海马在相对于正确拒绝和假装知道的错误识别过程中被激活。这些发现表明，功能磁共振成像可以检测出欺骗和错误记忆之间大脑活动的差异，尽管在这两个过程中，受试者对新事件的反应都是“我知道”。
We used functional magnetic resonance imaging (fMRI) to determine whether neural activity can differentiate between true memory, false memory, and deception. Subjects heard a series of semantically related words and were later asked to make a recognition judgment of old words, semantically related nonstudied words (lures for false recognition), and unrelated new words. They were also asked to make a deceptive response to half of the old and unrelated new words. There were 3 main findings. First, consistent with the notion that executive function supports deception, 2 types of deception (pretending to know and pretending not to know) recruited prefrontal activity. Second, consistent with the sensory reactivation hypothesis, the difference between true recognition and false recognition was found in the left temporoparietal regions probably engaged in the encoding of auditorily presented words. Third, the left prefrontal cortex was activated during pretending to know relative to correct rejection and false recognition, whereas the right anterior hippocampus was activated during false recognition relative to correct rejection and pretending to know. These findings indicate that fMRI can detect the difference in brain activity between deception and false memory despite the fact that subjects respond with “I know” to novel events in both processes.
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影响因子：
3.2
作者：
Abe, Nobuhito;Suzuki, Maki;Fujii, Toshikatsu
通讯作者：
Fujii, Toshikatsu
影响因子：
5.7
作者：
Johnson, Ray, Jr.;Henkell, Heather;Zhu, John
通讯作者：
Zhu, John
影响因子：
5.7
作者：
Chua, EF;Schacter, DL;Sperling, RA
通讯作者：
Sperling, RA
影响因子：
3.7
作者：
Ganis, G;Kosslyn, SM;Yurgelun-Todd, DA
通讯作者：
Yurgelun-Todd, DA
影响因子：
5.7
作者：
Davatzikos, C;Ruparel, K;Langleben, DD
通讯作者：
Langleben, DD