Twenty-Year Reflection on the Impact of World Trade Center Exposure on Pulmonary Outcomes in Fire Department of the City of New York (FDNY) Rescue and Recovery Workers.
Twenty-Year Reflection on the Impact of World Trade Center Exposure on Pulmonary Outcomes in Fire Department of the City of New York (FDNY) Rescue and Recovery Workers.
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DOI：
10.1007/s00408-021-00493-z
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发表时间：
2021-12
期刊：
影响因子：
5
通讯作者：
Prezant DJ
中科院分区：
文献类型：
--
作者：
Cleven KL;Rosenzvit C;Nolan A;Zeig-Owens R;Kwon S;Weiden MD;Skerker M;Halpren A;Prezant DJ
在2001年9月11日（9/11）的恐怖袭击之后，许多救援/恢复工作人员由于他们广泛的世界贸易中心（WTC）尘云暴露而出现呼吸道症状和肺部疾病。几乎所有的纽约市消防局（FDNY）的工作人员都在9/11事件发生后的48小时内以及接下来的几个月里出现在现场。由于纽约消防局在9/11之前为其消防员和紧急医疗服务人员提供了完善的职业健康服务，因此纽约消防局能够立即对其接触WTC的工人启动严格的监测和治疗计划。因此，呼吸道症状和疾病在9/11后不久就被发现了。这篇重点综述总结了9/11事件后纽约FDNY队列中发生的WTC相关呼吸系统疾病，包括WTC咳嗽综合征、阻塞性气道疾病、肺功能加速下降、气道高反应性、结节病和阻塞性睡眠呼吸暂停。此外，已确定大量生物标志物与WTC相关的呼吸道疾病相关。未来的研究工作不仅将集中在进一步的表型/治疗WTC相关的呼吸系统疾病，而且还将集中在与WTC暴露相关的其他疾病上，特别是那些需要几十年才能发展的疾病，如心血管疾病，癌症和间质性肺病。
After the terrorist attacks on September 11, 2001 (9/11), many rescue/recovery workers developed respiratory symptoms and pulmonary diseases due to their extensive World Trade Center (WTC) dust cloud exposure. Nearly all Fire Department of the City of New York (FDNY) workers were present within 48 h of 9/11 and for the next several months. Since the FDNY had a well-established occupational health service for its firefighters and Emergency Medical Services workers prior to 9/11, the FDNY was able to immediately start a rigorous monitoring and treatment program for its WTC-exposed workers. As a result, respiratory symptoms and diseases were identified soon after 9/11. This focused review summarizes the WTC-related respiratory diseases that developed in the FDNY cohort after 9/11, including WTC cough syndrome, obstructive airways disease, accelerated lung function decline, airway hyperreactivity, sarcoidosis, and obstructive sleep apnea. Additionally, an extensive array of biomarkers has been identified as associated with WTC-related respiratory disease. Future research efforts will not only focus on further phenotyping/treating WTC-related respiratory disease but also on additional diseases associated with WTC exposure, especially those that take decades to develop, such as cardiovascular disease, cancer, and interstitial lung disease.
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影响因子：
4.1
作者：
Crowley G;Kwon S;Haider SH;Caraher EJ;Lam R;St-Jules DE;Liu M;Prezant DJ;Nolan A
通讯作者：
Nolan A
影响因子：
4.3
作者：
Crowley G;Kim J;Kwon S;Lam R;Prezant DJ;Liu M;Nolan A
通讯作者：
Nolan A
影响因子：
9.6
作者：
Banauch, Gisela I.;Brantly, Mark;Prezant, David J.
通讯作者：
Prezant, David J.
DOI：
10.3390/ijerph16101830
发表时间：
2019-05-02
影响因子：
--
作者：
Cleven, Krystal L.;Ye, Kenny;Prezant, David J.
通讯作者：
Prezant, David J.
影响因子：
9.6
作者：
Cleven, Krystal L.;Vaeth, Brandon;Prezant, David J.
通讯作者：
Prezant, David J.