Managing overweight and obesity in adults to reduce cardiovascular disease risk.
Managing overweight and obesity in adults to reduce cardiovascular disease risk.
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DOI：
10.1007/s11883-014-0445-x
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发表时间：
2014-10
影响因子：
5.8
通讯作者：
Jensen, Michael D.
中科院分区：
文献类型：
--
作者：
Ebbert, Jon O.;Elrashidi, Muhamad Y.;Jensen, Michael D.
关键词：
肥胖是全球死亡和残疾的主要可预防原因。肥胖会增加临床可识别的心血管疾病 (CVD) 以及许多其他代谢、睡眠和骨科疾病危险因素的风险。需要采取协调和系统的干预措施来控制肥胖并降低这些风险。 Obesity 2 专家小组更新了之前的指南，并制定了“成人超重和肥胖管理指南”。该小组使用 1999 年至 2011 年出版物中的数据来解决五个关键问题，提供证据陈述，并建议创建治疗算法来指导临床护理决策。当前的综述讨论了与超重和肥胖患者评估和管理中的 CVD 风险相关的证据陈述。我们总结了 FDA 批准的用于治疗超重和肥胖的药物及其对 CVD 风险和危险因素的影响，以及正在进行的临床试验，这将进一步为临床实践提供信息。
Obesity is a leading preventable cause of death and disability worldwide. Obesity increases the risk for clinically identifiable risk factors for cardiovascular disease (CVD) as well as a host of other metabolic, sleep, and orthopedic disorders. Coordinated and systematic interventions are needed to manage obesity and reduce these risks. The Obesity 2 Expert Panel updated previous guidelines and produced the “Guideline for the Management of Overweight and Obesity in Adults.” The Panel used data from publications from years 1999 to 2011 to address five critical questions, provide evidence statements, and recommend creation of a treatment algorithm to guide decision making about clinical care. The current review discusses the evidence statements pertaining to CVD risk in the assessment and management of patients who are overweight and obese. We summarize the FDA-approved medications for the treatment of overweight and obesity and their impact on CVD risk and risk factors, as well as ongoing clinical trials which will further inform clinical practice.
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DOI：
10.1038/oby.2003.78
发表时间：
2003-04-01
期刊：
OBESITY RESEARCH
影响因子：
--
作者：
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通讯作者：
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影响因子：
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作者：
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DOI：
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发表时间：
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期刊：
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影响因子：
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影响因子：
120.7
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通讯作者：
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DOI：
10.3945/ajcn.111.024927
发表时间：
2012-02
期刊：
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影响因子：
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作者：
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通讯作者：
Bowden CH