Pluronic micelles encapsulated curcumin manifests apoptotic cell death and inhibits pro‐inflammatory cytokines in human breast adenocarcinoma cells

Pluronic micelles encapsulated curcumin manifests apoptotic cell death and inhibits pro‐inflammatory cytokines in human breast adenocarcinoma cells
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封装姜黄素的 Pluronic 胶束表现出细胞凋亡并抑制人乳腺癌细胞中的促炎细胞因子

DOI:
10.1002/cnr2.1133
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发表时间:
2018
期刊:
影响因子:
1.7
通讯作者:
C. Pathak
C. Pathak
中科院分区:
--
文献类型:
--
作者:
F. Vaidya;Rakesh K. Sharma;Sofiya J. Shaikh;D. Ray;V. Aswal;C. Pathak

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姜黄素是一种天然衍生物,具有广谱的生物活性,包括抗氧化,抗炎和抗癌。自古以来,它被用于治疗各种疾病。许多报道强调了其作为化学预防剂和化学治疗剂的潜力。尽管其具有必要的性质,但由于在水性介质中的低溶解度、有限的组织吸收和在生理pH下的快速降解,药理学应用受到限制。
Curcumin is a natural derivative, which exhibits broad spectrum biological activities including anti‐oxidant, anti‐inflammatory, and anti‐cancer. Since ancient times, it has been used for the treatment of various diseases. Many reports highlighted its potential as a chemopreventive and chemotherapeutic agent. Despite its imperative properties, the pharmacological application had been limited due to low solubility in the aqueous medium, limited tissue absorption, and rapid degradation at physiological pH.
姜黄素纳米制剂:一种未来的纳米药物癌。
DOI: 10.1016/j.drudis.2011.09.009
发表时间: 2012-01
影响因子: 7.4
作者:
Yallapu, Murali M.;Jaggi, Meena;Chauhan, Subhash C.
通讯作者: Chauhan, Subhash C.
DOI: 10.1016/j.jhep.2015.04.018
发表时间: 2015-09
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