Marker-free lung tumor trajectory estimation from a cone beam CT sinogram.
Marker-free lung tumor trajectory estimation from a cone beam CT sinogram.
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DOI：
10.1088/0031-9155/55/9/014
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发表时间：
2010-05-07
影响因子：
3.5
通讯作者：
Yan D
中科院分区：
文献类型：
--
作者：
Hugo GD;Liang J;Yan D
提出了一种利用锥束CT正弦图的投影数据和模板配准方法来估计三维肺肿瘤位置的算法。使用预先存在的呼吸相关CT图像来生成目标的模板，然后将其配准到各个锥形束CT投影，并对每个投影进行目标位置的估计。基于锥形束CT扫描采集期间的平均肿瘤位置的知识，限制配准搜索区域。比较了几种模板配准算法，包括相关系数法和鲁棒的块相关法、鲁棒相关系数法和鲁棒梯度相关法。发现稳健的配准指标对闭塞（例如覆盖组织和治疗床）不太敏感。采用稳健配准算法，体模中位置估计的平均精度为1.4 mm。在两名外周肿瘤研究受试者中，与使用4D图像体积的“4D”配准获得的结果相比，平均位置和平均目标偏移估计在2.0 mm以内。
An algorithm was developed to estimate the 3D lung tumour position using the projection data forming a cone beam CT sinogram and a template registration method. A pre-existing respiration-correlated CT image was used to generate templates of the target, which were then registered to the individual cone beam CT projections, and estimates of the target position were made for each projection. The registration search region was constrained based on knowledge of the mean tumour position during the cone beam CT scan acquisition. Several template registration algorithms were compared, including correlation coefficient and robust methods such as block correlation, robust correlation coefficient, and robust gradient correlation. Robust registration metrics were found to be less sensitive to occlusions such as overlying tissue and the treatment couch. Mean accuracy of the position estimation was 1.4 mm in phantom with a robust registration algorithm. In two research subjects with peripheral tumours, the mean position and mean target excursion were estimated to within 2.0 mm compared to the results obtained with a ‘4D’ registration of 4D image volumes.
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影响因子：
3.5
作者：
Chan, TCY;Bortfeld, T;Tsitsiklis, JN
通讯作者：
Tsitsiklis, JN
影响因子：
3.8
作者：
Trofimov, Alexei;Vrancic, Christian;Bortfeld, Thomas
通讯作者：
Bortfeld, Thomas
DOI：
10.1016/j.ijrobp.2008.06.1937
发表时间：
2008-11-15
影响因子：
7
作者：
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通讯作者：
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影响因子：
3.5
作者：
Marchant, T. E.;Amer, A. M.;Moore, C. J.
通讯作者：
Moore, C. J.
影响因子：
3.5
作者：
Trofimov, A;Rietzel, E;Bortfeld, T
通讯作者：
Bortfeld, T