Retrospective analysis of artifacts in four-dimensional CT images of 50 abdominal and thoracic radiotherapy patients.
Retrospective analysis of artifacts in four-dimensional CT images of 50 abdominal and thoracic radiotherapy patients.
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DOI：
10.1016/j.ijrobp.2008.06.1937
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发表时间：
2008-11-15
影响因子：
7
通讯作者：
Keall, Paul J.
中科院分区：
文献类型：
--
作者：
Yamamoto, Tokihiro;Langner, Ulrich;Loo, Billy W., Jr.;Shen, John;Keall, Paul J.
量化使用多层电影方法采集的四维 (4D) CT 图像中伪影的类型、频率和幅度。本研究纳入了 50 名连续接受 4D-CT 扫描和胸部或腹部癌症放射治疗的患者。所有 4D-CT 扫描均在 GE 多层 PET/CT 扫描仪上进行，并采用电影模式的瓦里安 RPM 系统。 GE Advantage 4D 软件用于创建 4D-CT 数据集。然后对这些伪影进行视觉和定量分析。我们进一步进行了统计分析，以评估患者或呼吸模式相关参数与伪影的发生和程度之间的关系。结果发现，50 名患者中有 45 名 (90%) 在膈肌或心脏中至少有一个伪影（模糊除外），平均大小为 11.6 毫米（范围为 4.4 – 56.0 毫米）。我们还在 20 个肺部或纵隔肿瘤中的 6 个（30%）中观察到至少一种伪影。统计分析显示，有伪影和无伪影的患者亚组中，几个呼吸模式相关参数之间存在显着差异，包括腹部位移 (p < 0.01)。研究发现，伪影的大小与两个相邻床位之间的腹部位移差异显着但微弱相关（R = 0.34，p < 0.01）。这项研究发现 4D-CT 中伪影的频率和严重程度高得惊人。 4D-CT 成像需要显着改进。
To quantify the type, frequency and magnitude of artifacts in four-dimensional (4D) CT images acquired using a multislice cine method. Fifty consecutive patients, who underwent 4D-CT scanning and radiotherapy for thoracic or abdominal cancers, were included in this study. All the 4D-CT scans were performed on the GE multislice PET/CT scanner with the Varian RPM system in cine mode. The GE Advantage 4D software was used to create 4D-CT data sets. The artifacts were then visually and quantitatively analyzed. We further performed statistical analyses to evaluate the relationships between patient- or breathing pattern-related parameters and the occurrence as well as magnitude of artifacts. It was found that 45 of 50 patients (90%) had at least one artifact (other than blurring) with a mean magnitude of 11.6 mm (range, 4.4 – 56.0 mm) in the diaphragm or heart. We also observed at least one artifact in 6 of 20 lung or mediastinal tumors (30%). Statistical analysis revealed that there were significant differences between several breathing pattern-related parameters, including abdominal displacement (p < 0.01), for the subgroups of patients with and without artifacts. The magnitude of an artifact was found to be significantly but weakly correlated with the abdominal displacement difference between two adjacent couch positions (R = 0.34, p < 0.01). This study has identified that the frequency and magnitude of artifacts in 4D-CT is alarmingly high. Significant improvement is needed in 4D-CT imaging.
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DOI：
10.1016/j.ijrobp.2006.02.035
发表时间：
2006-07-01
影响因子：
7
作者：
George, Rohini;Chung, Theodore D.;Keall, Paul J.
通讯作者：
Keall, Paul J.
DOI：
10.1007/bf03178368
发表时间：
2002-03-01
影响因子：
--
作者：
Keall, P. J.;Kini, V. R.;Mohan, R.
通讯作者：
Mohan, R.
影响因子：
3.8
作者：
Mori, S;Endo, M;Kusakabe, M
通讯作者：
Kusakabe, M
影响因子：
3.8
作者：
Mutaf, Y. D.;Antolak, J. A.;Brinkmann, D. H.
通讯作者：
Brinkmann, D. H.
DOI：
10.1016/s0360-3016(98)00130-8
发表时间：
1998-07-01
影响因子：
7
作者：
Balter, JM;Lam, KL;Ten Haken, RK
通讯作者：
Ten Haken, RK