Capillary flow control using hydrophobic patterns

Capillary flow control using hydrophobic patterns
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使用疏水模式控制毛细管流量

DOI:
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发表时间:
2007
期刊:
影响因子:
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通讯作者:
Jun
Jun
中科院分区:
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文献类型:
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作者:
J. Suk;Jun

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本文介绍了一种简单的方法来控制自主毛细管流动的速度,使用一系列疏水模式。本文所述的微流控系统由两个由间隔片隔开的平行平面板组成。底板有亲水性微通道,微通道周围有疏水轨迹。与底板相比,顶表面相对疏水。这些疏水轨迹和微通道中间的疏水图案使用PDMS图章通过接触印刷进行图版。通过控制疏水面积占整个通道宽度的比例和两板之间的距离,可以控制特定位置的毛细管流速。利用这种方法,期望利用毛细管流在微流控装置中实现足够的生物反应潜伏期。
This note presents a simple method to control the speed of the autonomous capillary flow using an array of hydrophobic patterns. The microfluidic system in this note was composed of two planar parallel plates that were separated by spacers. The bottom plate had a hydrophilic microchannel which was surrounded by hydrophobic tracks. The top surface was relatively hydrophobic compared to the bottom plate. These hydrophobic tracks and the hydrophobic patterns in the middle of the microchannels were patterned using PDMS stamps by contact printing. By controlling the ratio of hydrophobic area to the whole channel width and the distance between two plates, it was possible to control the capillary flow speed at specific positions. Using this method, it is expected to achieve a sufficient incubation time for biological reactions in microfluidic devices using the capillary flow.
DOI: 10.1126/science.288.5463.113
发表时间: 2000-04-07
期刊: SCIENCE
影响因子: 56.9
作者:
Unger, MA;Chou, HP;Quake, SR
通讯作者: Quake, SR