Effect of castration on the turnover of rat liver alcohol dehydrogenase.
Effect of castration on the turnover of rat liver alcohol dehydrogenase.
复制标题
去势对大鼠肝脏乙醇脱氢酶周转的影响。
DOI:
10.1016/0006-2952(85)90045-0
复制
发表时间:
1985
影响因子:
5.8
通讯作者:
Potter,JJ
中科院分区:
文献类型:
--
作者:
Mezey,E;Potter,JJ
Castration increased liver alcohol dehydrogenase activity and enzyme protein in male rats. The turnover of alcohol dehydrogenase determined from the decline in radioactivity present in immunoprecipitated enzyme after injection of NaH14CO3was decreased after castration. The fractional rate of degradation (Kd) for the enzyme was 0.11 · day−1in the castrated as compared with 0.13 · day−1in the control animals (P < 0.05). The fractional rate of synthesis (Ks) of the enzyme was not affected by castration, while the absolute rate of synthesis was increased slightly. This study shows that a decrease in the rate of degradation is the principal cause for the increase in liver alcohol dehydrogenase following castration.
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影响因子:
5.8
作者:
E. Mezey;J. Potter;R. Květňanský
通讯作者:
R. Květňanský
影响因子:
29.4
作者:
E. Mezey;J. Potter
通讯作者:
J. Potter
影响因子:
4.8
作者:
E. Mezey;J. Potter
通讯作者:
J. Potter
影响因子:
--
作者:
S. Mccann;L. Krulich;P. Illner;M. Quijada;K. Ajika;C. Fawcett
通讯作者:
C. Fawcett
影响因子:
5.8
作者:
Gerald Weissmann
通讯作者:
Gerald Weissmann