Preparation, characterization, and antifungal activity of hymexazol-linked chitosan derivatives

Preparation, characterization, and antifungal activity of hymexazol-linked chitosan derivatives
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恶霉唑连接的壳聚糖衍生物的制备、表征及其抗真菌活性

DOI:
10.1007/s00343-017-6100-y
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发表时间:
2017-09
影响因子:
--
通讯作者:
XING Rong’e
XING Rong’e
中科院分区:
地学4区
文献类型:
--
作者:
QIN Yukun;LIU Song;LI Pengcheng;XING Rong’e

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本文合成了三种恶霉唑连接的壳聚糖衍生物(HML-CS),并通过红外光谱和元素分析对其结构进行了表征。通过高效液相色谱法测量连接比。研究了100、200和400 mg/L浓度下化合物对植物病原真菌Rhizoctonia solaniCGMCC3.28和Gibberella zeaeCGMCC3.42的抑菌活性。这些HML-CS衍生物表现出更强的抗真菌活性比CS单独。HML-CS-1对G.在400 mg/L浓度下,玉米的抑菌指数为65.9%,对小麦赤星病菌的抑菌活性最强。在400 mg/L浓度下,其抑菌指数为52.7%。这种共轭CS和HML建议部分之间的协同效应的存在下,并表明这些衍生物具有很大的潜力,作为新的杀菌剂,并需要进一步的研究,在作物保护中的应用开发。
In this study, three hymexazol-linked chitosan derivatives (HML-CS) were synthesized and their structures confirmed by Fourier transform infrared and elemental analysis. Linkage ratios were measured by high performance liquid chromatography. The derivatives’ antifungal activity against the plant pathogenic fungiRhizoctonia solaniCGMCC 3.28 andGibberella zeaeCGMCC 3.42 were investigated at concentrations of 100, 200, and 400 mg/L. These HML-CS derivatives exhibited stronger antifungal activity than CS alone. HML-CS-1 showed the best antifungal activity againstG. zeae, whose antifungal index was 65.9% at 400 mg/L, and also showed the best antifungal activity againstR. solani, whose antifungal index was 52.7% at 400 mg/L. This conjugation of CS and HML suggested the presence of synergistic effects between the moieties and indicated that these derivatives possessed great potential as novel fungicides and require further research for the development of applications in crop protection.
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