Differential Risk of SARS-CoV-2 Infection by Occupation: Evidence from the Virus Watch prospective cohort study in England and Wales.
Differential Risk of SARS-CoV-2 Infection by Occupation: Evidence from the Virus Watch prospective cohort study in England and Wales.
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DOI：
10.1186/s12995-023-00371-9
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发表时间：
2023-04-03
影响因子：
3
通讯作者：
Hayward, Andrew
中科院分区：
文献类型：
--
作者：
Beale, Sarah;Hoskins, Susan;Byrne, Thomas;Fong, Wing Lam Erica;Fragaszy, Ellen;Geismar, Cyril;Kovar, Jana;Navaratnam, Annalan M. D.;Nguyen, Vincent;Patel, Parth;Yavlinsky, Alexei;Johnson, Anne;Van Tongeren, Martie;Aldridge, Robert;Hayward, Andrew
不同职业的工人感染SARS-CoV-2的风险不同，但职业对这种关系的直接贡献尚不清楚。这项研究旨在调查截至2022年4月，英格兰和威尔士职业群体之间的感染风险差异，并根据流行阶段调整潜在的混杂因素和分层。 来自Virus Watch前瞻性队列研究的15，190名受雇/自雇参与者的数据被用于使用稳健的泊松回归生成病毒学或血清学确认的SARS-CoV-2感染的风险比，调整社会人口统计学和健康相关因素以及非工作公共活动。我们根据调整后的风险比（aRR）计算了暴露于每个职业组的归因分数（AF）。在护士中发现风险增加（aRR = 1.44，1.25-1.65; AF = 30%，20-39%），医生（aRR = 1.33，1.08-1.65; AF = 25%，7-39%），照顾者（1.45，1.19-1.76; AF = 31%，16-43%），小学教师（aRR = 1.67，1.42- 1.96; AF = 40%，30-49%），中学教师（aRR = 1.48，1.26-1.72; AF = 32%，21-42%）和教学支持职业（aRR = 1.42，1.23-1.64; AF = 29%，18-39%）相比，办公室为基础的专业职业。对于大多数群体来说，早期阶段（2020年2月至2021年5月）的差异风险明显，随后（2021年6月至10月）减弱，尽管教师和教学支持人员在各波中表现出持续升高的风险。SARS-CoV-2感染风险的职业差异随时间而变化，并对社会人口统计学，健康相关和非工作场所活动相关的潜在混杂因素进行调整。需要直接调查导致风险升高的工作场所因素以及这些因素如何随着时间的推移而变化，以告知职业健康干预措施。 在线版本包含补充材料，可通过10.1186/s12995-023-00371-9获得。
Workers across different occupations vary in their risk of SARS-CoV-2 infection, but the direct contribution of occupation to this relationship is unclear. This study aimed to investigate how infection risk differed across occupational groups in England and Wales up to April 2022, after adjustment for potential confounding and stratification by pandemic phase. Data from 15,190 employed/self-employed participants in the Virus Watch prospective cohort study were used to generate risk ratios for virologically- or serologically-confirmed SARS-CoV-2 infection using robust Poisson regression, adjusting for socio-demographic and health-related factors and non-work public activities. We calculated attributable fractions (AF) amongst the exposed for belonging to each occupational group based on adjusted risk ratios (aRR). Increased risk was seen in nurses (aRR = 1.44, 1.25–1.65; AF = 30%, 20–39%), doctors (aRR = 1.33, 1.08–1.65; AF = 25%, 7–39%), carers (1.45, 1.19–1.76; AF = 31%, 16–43%), primary school teachers (aRR = 1.67, 1.42- 1.96; AF = 40%, 30–49%), secondary school teachers (aRR = 1.48, 1.26–1.72; AF = 32%, 21–42%), and teaching support occupations (aRR = 1.42, 1.23–1.64; AF = 29%, 18–39%) compared to office-based professional occupations. Differential risk was apparent in the earlier phases (Feb 2020—May 2021) and attenuated later (June—October 2021) for most groups, although teachers and teaching support workers demonstrated persistently elevated risk across waves. Occupational differences in SARS-CoV-2 infection risk vary over time and are robust to adjustment for socio-demographic, health-related, and non-workplace activity-related potential confounders. Direct investigation into workplace factors underlying elevated risk and how these change over time is needed to inform occupational health interventions. The online version contains supplementary material available at 10.1186/s12995-023-00371-9.
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影响因子：
3.5
作者：
Zhang, Michael
通讯作者：
Zhang, Michael
影响因子：
--
作者：
Pearce, Neil;Rhodes, Sarah;van Tongeren, Martie
通讯作者：
van Tongeren, Martie
DOI：
10.2807/1560-7917.es.2020.25.50.2001884
发表时间：
2020-12
期刊：
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
影响因子：
--
作者：
de Gier B;de Oliveira Bressane Lima P;van Gaalen RD;de Boer PT;Alblas J;Ruijten M;van Gageldonk-Lafeber AB;Waegemaekers T;Schreijer A;van den Hof S;Hahné SJ
通讯作者：
Hahné SJ
DOI：
10.2807/1560-7917.es.2021.26.40.2001875
发表时间：
2021-10
期刊：
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
影响因子：
--
作者：
Magnusson K;Nygård K;Methi F;Vold L;Telle K
通讯作者：
Telle K
影响因子：
3.7
作者：
Fogh K;Strange JE;Scharff BFSS;Eriksen ARR;Hasselbalch RB;Bundgaard H;Nielsen SD;Jørgensen CS;Erikstrup C;Norsk J;Nielsen PB;Kristensen JH;Østergaard L;Ellermann-Eriksen S;Andersen B;Nielsen H;Johansen IS;Wiese L;Simonsen L;Fischer TK;Folke F;Lippert F;Ostrowski SR;Benfield T;Mølbak K;Ethelberg S;Koch A;Sönksen UW;Vangsted AM;Krause TG;Fomsgaard A;Ullum H;Skov R;Iversen K
通讯作者：
Iversen K