Light-dependent spin trapping of hydroxyl radical from human erythrocytes.
Light-dependent spin trapping of hydroxyl radical from human erythrocytes.
复制标题
人红细胞中羟基自由基的光依赖性自旋捕获。
DOI:
10.1016/0006-291x(91)91715-o
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发表时间:
1991
影响因子:
3.1
通讯作者:
Rosen,GM
中科院分区:
文献类型:
--
作者:
Bynoe,LA;Pou,S;Gottsch,JD;Rosen,GM
The generation of reactive oxygen species from human erythrocytes has previously been demonstrated. Furthermore, erythrocytic protoporphyrin IX has been shown to generate superoxide and singlet oxygen when exposed to light. These findings suggest that a component of erythrocytic reactive oxygen species production may be light-dependent. By inhibiting erythrocyte superoxide dismutase, catalase, and glutathione peroxidase withN,N-diethyldithiocarbamate or sodium cyanide, we demonstrate the light-dependent generation of hydroxyl radical in human erythrocytes using spin trapping/Electron Spin Resonance spectroscopy. This finding may be significant in tissues where blood is exposed to light, such as in the eye.
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DOI:
--
发表时间:
1959
期刊:
影响因子:
--
作者:
R. Bonnett;R. F. Brown;V. M. Clark;I. Sutherland;A. Todd
通讯作者:
A. Todd
影响因子:
158.5
作者:
P. Glass;G. Avery;K. N. Subramanian;M. Keys;A. Sostek;D. Friendly
通讯作者:
D. Friendly
影响因子:
2.9
作者:
S. Pou;D. Hassett;B. Britigan;M. Cohen;G. Rosen
通讯作者:
S. Pou;D. Hassett;B. Britigan;M. Cohen;G. Rosen
影响因子:
3.5
作者:
G. Buettner;L. Oberley
通讯作者:
L. Oberley
影响因子:
3.3
作者:
BUETTNER, GR;OBERLEY, LW;LEUTHAUSER, SWHC
通讯作者:
LEUTHAUSER, SWHC