Percutaneous cryoablation of pulmonary metastases from colorectal cancer.
Percutaneous cryoablation of pulmonary metastases from colorectal cancer.
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DOI：
10.1371/journal.pone.0027086
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发表时间：
2011
期刊：
影响因子：
3.7
通讯作者：
Nomori H
中科院分区：
文献类型：
--
作者：
Yamauchi Y;Izumi Y;Kawamura M;Nakatsuka S;Yashiro H;Tsukada N;Inoue M;Asakura K;Nomori H
目的评价冷冻消融治疗结直肠癌转移性肺肿瘤的安全性和有效性。24例患者（年龄36-82岁，中位年龄62岁；17例男性，7例女性）在30个疗程中进行了55例肺转移性肿瘤手术。通过每3-4个月进行一次随访的计算机断层扫描来评估手术安全性、局部无进展间隔和总生存期。主要并发症为气胸19例（63%），胸腔积液21例（70%），一过性自限性咯血13例（43%），尿路播散1例（3%）。1年和3年局部无进展间隔分别为90.8%和59%。直径≤15mm的肿瘤3年局部无进展间隔为79.8%，直径≤15mm的肿瘤3年局部无进展间隔为28.6% （p = 0.001， log-rank检验）。1年和3年总生存率分别为91%和59.6%。结果表明经皮冷冻消融是一种可行的治疗方法。至少对于直径≤15mm的肿瘤，局部无进展间隔是令人满意的。
To evaluate the safety and efficacy of cryoablation for metastatic lung tumors from colorectal cancer. The procedures were performed on 24 patients (36–82 years of age, with a median age of 62; 17 male patients, 7 female patients) for 55 metastatic tumors in the lung, during 30 sessions. The procedural safety, local progression free interval, and overall survival were assessed by follow-up computed tomographic scanning performed every 3–4 months. The major complications were pneumothorax, 19 sessions (63%), pleural effusion, 21 sessions (70%), transient and self-limiting hemoptysis, 13 sessions (43%) and tract seeding, 1 session (3%). The 1- and 3-year local progression free intervals were 90.8% and 59%, respectively. The 3-years local progression free intervals of tumors ≤15 mm in diameter was 79.8% and that of tumors >15 mm was 28.6% (p = 0.001; log-rank test). The 1- and 3-year overall survival rates were 91% and 59.6%, respectively. The results indicated that percutaneous cryoablation is a feasible treatment option. The local progression free interval was satisfactory at least for tumors that were ≤15 mm in diameter.
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DOI：
10.1016/j.jtcvs.2004.10.019
发表时间：
2005-03-01
影响因子：
6
作者：
Fernando, HC;De Hoyos, A;Luketich, JD
通讯作者：
Luketich, JD
影响因子：
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作者：
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通讯作者：
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DOI：
10.1016/j.jtcvs.2005.12.051
发表时间：
2006-05-01
影响因子：
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DOI：
10.1016/j.jvir.2007.06.027
发表时间：
2007-10-01
影响因子：
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作者：
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影响因子：
5
作者：
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