KrakenUniq: confident and fast metagenomics classification using unique k-mer counts.
KrakenUniq: confident and fast metagenomics classification using unique k-mer counts.
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DOI:
10.1186/s13059-018-1568-0
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发表时间:
2018-11-16
期刊:
影响因子:
12.3
通讯作者:
Salzberg SL
中科院分区:
文献类型:
--
作者:
Breitwieser FP;Baker DN;Salzberg SL
False-positive identifications are a significant problem in metagenomics classification. We present KrakenUniq, a novel metagenomics classifier that combines the fast k-mer-based classification of Kraken with an efficient algorithm for assessing the coverage of unique k-mers found in each species in a dataset. On various test datasets, KrakenUniq gives better recall and precision than other methods and effectively classifies and distinguishes pathogens with low abundance from false positives in infectious disease samples. By using the probabilistic cardinality estimator HyperLogLog, KrakenUniq runs as fast as Kraken and requires little additional memory. KrakenUniq is freely available at https://github.com/fbreitwieser/krakenuniq. The online version of this article (10.1186/s13059-018-1568-0) contains supplementary material, which is available to authorized users.
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影响因子:
12.3
作者:
McIntyre ABR;Ounit R;Afshinnekoo E;Prill RJ;Hénaff E;Alexander N;Minot SS;Danko D;Foox J;Ahsanuddin S;Tighe S;Hasan NA;Subramanian P;Moffat K;Levy S;Lonardi S;Greenfield N;Colwell RR;Rosen GL;Mason CE
通讯作者:
Mason CE
DOI:
10.1016/j.jinf.2017.12.014
发表时间:
2018-03
期刊:
The Journal of infection
影响因子:
--
作者:
Brown JR;Bharucha T;Breuer J
通讯作者:
Breuer J
DOI:
10.1093/bioinformatics/btt389
发表时间:
2013-09-15
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Ames SK;Hysom DA;Gardner SN;Lloyd GS;Gokhale MB;Allen JE
通讯作者:
Allen JE
影响因子:
4.3
作者:
Huson DH;Beier S;Flade I;Górska A;El-Hadidi M;Mitra S;Ruscheweyh HJ;Tappu R
通讯作者:
Tappu R
影响因子:
4.4
作者:
Ounit R;Wanamaker S;Close TJ;Lonardi S
通讯作者:
Lonardi S