High magnification in situ viewing of wound healing in oral mucosa.
High magnification in situ viewing of wound healing in oral mucosa.
复制标题
高倍放大原位观察口腔粘膜伤口愈合情况。
DOI：
--
复制
发表时间：
1996
影响因子：
2.1
通讯作者：
Gregory J. Seymour
中科院分区：
文献类型：
--
作者：
Laurence J. Walsh;Peter L'Estrange;Gregory J. Seymour
显微镜内窥镜是一种允许对软组织进行高分辨率、非侵入性检查的技术。本研究采用显微镜内窥镜检查口腔粘膜暴露于二氧化碳激光辐射后的愈合过程。在伤口边界，细胞碎片和激光诱导的炭化层脱落上皮细胞迁移发生。伤口二期愈合，72小时时上皮完全闭合。在受伤后6至48小时，明显的血管反应是明显的，这一时间段与已知的血管活化和白细胞浸润伤口部位的模式一致。使用显微镜内窥镜作为辅助活检和其他侵入性诊断方法在评估和随访软组织病理可能有价值的临床实践。
Microscope endoscopy is a technique which allows high resolution, non-invasive examination of soft tissues. This study employed microscope endoscopy to examine the process of healing following exposure of the oral mucosa to carbon dioxide laser radiation. On the wound boundaries, cellular debris and the laser-induced char layer were shed as epithelial migration occurred. Wounds healed by secondary intention, with complete epithelial closure by 72 hours. A marked vascular response was evident from 6 to 48 hours following wounding, a time period coincident with the known pattern of blood vessel activation and infiltration of the wound site by leukocytes. The use of microscope endoscopy as an adjunct to biopsy and other invasive diagnostic methods in the assessment and follow-up of soft tissue pathology may have value in clinical practice.
DOI：
10.1073/pnas.88.10.4220
发表时间：
1991-05-01
影响因子：
11.1
作者：
WALSH, LJ;TRINCHIERI, G;MURPHY, GF
通讯作者：
MURPHY, GF
皮肤免疫细胞运输的决定因素。
DOI：
--
发表时间：
1990
期刊：
Laboratory investigation; a journal of technical methods and pathology
影响因子：
--
作者：
Walsh,LJ;Lavker,RM;Murphy,GF
通讯作者：
Murphy,GF