Optical coherence tomography accurately measures corneal power change from laser refractive surgery.

Optical coherence tomography accurately measures corneal power change from laser refractive surgery.
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DOI:
10.1016/j.ophtha.2014.10.003
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发表时间:
2015-04
期刊:
影响因子:
13.7
通讯作者:
Kuo, Anthony N.
Kuo, Anthony N.
中科院分区:
医学1区
文献类型:
--
作者:
McNabb, Ryan P.;Farsiu, Sina;Stinnett, Sandra S.;Izatt, Joseph A.;Kuo, Anthony N.

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To determine the ability of motion corrected optical coherence tomography (OCT) to measure the corneal refractive power change due to laser in situ keratomileusis (LASIK). Evaluation of a diagnostic test or technology in a cohort. 70 eyes from 37 subjects undergoing LASIK were measured preoperatively. 39 eyes from 22 subjects were measured postoperatively and completed the study. Consecutive patients undergoing LASIK at the Duke Eye Center who consented to participate were imaged with Placido-ring topography, Scheimpflug photography and OCT on the day of their surgery. Patients were then reimaged with the same imaging systems at the post-operative month 3 visit. Change in pre- to post-operative corneal refractive power as measured by each of the imaging modalities was compared to the pre- to post-operative change in manifest refraction using t-test with generalized estimating equations. Corneal refractive power change due to LASIK as measured by Placido-ring topography, Scheimpflug Photography, and OCT compared to the manifest refraction change vertexed to the corneal plane. The change in manifest refraction should correspond to the change in the corneal refractive power from LASIK and was considered the reference measurement. In 22 returning post-LASIK individuals (39 eyes), we found no significant difference between the clinically measured pre to post LASIK change in manifest refraction and both Scheimpflug photography (p = 0.714) and OCT (p = 0.216). In contrast, keratometry values from Placido-ring topography were found to be significantly different from the measured refractive change (p < 0.001). Additionally, of the three imaging modalities, OCT recorded the smallest mean absolute difference from the reference measurement with the least amount of variability. Motion corrected OCT more accurately measures the change in corneal refractive power due to laser refractive surgery than currently available clinical devices. By offering accurate corneal refractive power measurements in normal and surgically modified subjects, OCT offers a compelling alternative to current clinical devices for determining corneal refractive power.
DOI: 10.1364/boe.3.002050
发表时间: 2012-09-01
影响因子: 3.4
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