Morphologic differences between the hips of Chinese women and white women: could they account for the ethnic difference in the prevalence of hip osteoarthritis?
Morphologic differences between the hips of Chinese women and white women: could they account for the ethnic difference in the prevalence of hip osteoarthritis?
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DOI：
10.1002/art.30472
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发表时间：
2011-10
影响因子：
--
通讯作者：
Felson, David T.
中科院分区：
文献类型：
--
作者：
Dudda, Marcel;Kim, Young-Jo;Zhang, Yuqing;Nevitt, Michael C.;Xu, Ling;Niu, Jingbo;Goggins, Joyce;Doherty, Michael;Felson, David T.
髋关节骨关节炎（OA）是一种常见的致残性疾病，白人的患病率远高于亚洲人。这种患病率种族差异的原因尚不清楚。髋关节OA通常被认为是继发于形态异常。如果特定的异常倾向于髋关节OA更频繁地发生在白人中，这些髋关节形状的差异可以解释患病率的差异。对来自2项研究的200名女性参与者的400个非骨关节炎髋关节进行了形态测量研究：北京OA研究和美国SOF研究。我们重点关注髋关节发育不良和撞击的测量（外侧中心边缘角、撞击角、髋臼斜率、股骨头颈比和交叉符号），并比较了中国人和白人髋关节的数据。与中国女性相比，白人女性的平均撞击角较低（83.6° vs. 87.0°，p= 0.03），并且更可能具有提示撞击的中心边缘角（对于中心边缘角>35°，11%的中国女性vs. 23%的白人髋关节，p = 0.008）。另一方面，低中心边缘角提示发育不良在中国女性中更常见（<20°，中国髋关节22% vs.高加索髋关节7%，p = 0.005）。在一项针对无OA体征的老年女性的研究中，撞击和非球面的形态测量在白人髋关节中比在中国髋关节中更常见。我们的研究结果表明，白种人可能比中国人髋关节骨性关节炎的风险更高，因为形态学的发现，使他们更容易股骨髋臼撞击。
Hip osteoarthritis (OA) is a common disabling disease, which has a much higher prevalence in Caucasians than Asians. The reasons for this ethnic difference in prevalence are unknown. Hip OA often is thought to be secondary to morphologic abnormalities. If particular abnormalities predisposing to hip OA occur more frequently in Caucasians, these differences in hip shape could account for prevalence differences. A morphometric study was performed using 400 non-osteoarthritic hips of 200 women participants from 2 studies: the Beijing OA study and the SOF study from the U.S. We focused on measures of hip dysplasia and impingement (Lateral Center Edge Angle, Impingement Angle, Acetabular Slope, Femoral Head Neck Ratio and the Cross Over Sign) and compared data from Chinese and Caucasian hips. Compared with their Chinese counterparts, Caucasian women had a lower mean impingement angle (83.6° vs. 87.0°’ p=.03) and were more likely to have center edge angles suggestive of impingement (for center edge angle >35°, 11% of Chinese vs. 23% of Caucasian hips, p = .008). On the other hand, low center edge angles suggesting dysplasia were found more often in Chinese women (for <20°, 22% of Chinese vs. 7% of Caucasian hips, p = .005). In a study of elderly women without signs of OA, the morphometry of impingement and asphericity were more common in Caucasian than Chinese hips. Our findings suggest that Caucasians may be at higher risk of hip OA than Chinese because of morphologic findings that predispose them to femoro-acetabular impingement.
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DOI：
10.1097/01.blo.0000096804.78689.c2
发表时间：
2003-12-01
影响因子：
4.2
作者：
Ganz, R;Parvizi, J;Siebenrock, KA
通讯作者：
Siebenrock, KA
DOI：
10.2106/00004623-197355030-00010
发表时间：
1973-01-01
影响因子：
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3.5
作者：
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通讯作者：
Ikegawa, S
影响因子：
--
作者：
Lanyon, P;Muir, K;Doherty, M
通讯作者：
Doherty, M
影响因子：
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作者：
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