Some characteristics of clinical sequelae of COVID-19 survivors from Wuhan, China: A multi-center longitudinal study.
Some characteristics of clinical sequelae of COVID-19 survivors from Wuhan, China: A multi-center longitudinal study.
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中国武汉市 COVID-19 幸存者临床后遗症的一些特征：多中心纵向研究
DOI：
10.1111/irv.12943
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发表时间：
2022-05
影响因子：
4.4
通讯作者：
Cen Y
中科院分区：
文献类型：
--
作者：
Chen X;Li Y;Shao TR;Yang LL;Li SJ;Wang XJ;Li A;Wu YY;Liu XF;Liu CM;Liu YH;Zeng F;Cen Y
COVID-19大流行对全球健康造成持续影响，但其后遗症需要在地球仪范围内广泛解决。本研究旨在调查COVID-19幸存者队列中中期（>6个月）临床后遗症的特征、患病率和风险因素。研究共纳入715名于2020年4月1日前从中国武汉三家医疗中心出院的COVID-19幸存者。纵向研究通过电话访谈进行，问卷调查包括一般，呼吸和心血管系统的临床后遗症。记录并分析幸存者的人口统计学资料和临床后遗症的一些特征。采用多因素Logistic回归分析探讨影响后遗症的危险因素。从出院到电话访谈的中位时间间隔为225.0天。COVID-19幸存者的中位年龄为69岁，51.3%为男性。其中29.9%有至少一种临床后遗症。分别有19.2%、22.7%和5.0%的幸存者报告疲劳、呼吸道症状和心血管症状。合并症、疾病严重程度、机械通气和高流量氧疗的应用以及再入院史与临床后遗症的存在相关。我们的研究为COVID-19幸存者临床后遗症的患病率和特征提供了进一步的证据，表明需要长期监测和管理才能使他们完全康复。
The pandemic of COVID‐19 has a persistent impact on global health, yet its sequelae need to be addressed at a wide scale around the globe. This study aims to investigate the characteristics, prevalence, and risk factors for mid‐term (>6 months) clinical sequelae in a cohort of COVID‐19 survivors. Totally 715 COVID‐19 survivors discharged before April 1, 2020, from three medical centers in Wuhan, China, were included. The longitudinal study was conducted by telephone interviews based on a questionnaire including the clinical sequelae of general, respiratory, and cardiovascular systems. Demographics and some characteristics of clinical sequelae of the survivors were recorded and analyzed. Multivariate logistic regression analysis was applied to explore the risk factors for the sequelae. The median time interval from discharge to telephone interview was 225.0 days. The COVID‐19 survivors' median ages were 69 years, and 51.3% were male. Among them, 29.9% had at least one clinical sequela. There were 19.2%, 22.7%, and 5.0% of the survivors reporting fatigue, respiratory symptoms, and cardiovascular symptoms, respectively. Comorbidities, disease severity, the application of mechanical ventilation and high‐flow oxygen therapy, and the history of re‐admission were associated with the presence of clinical sequelae. Our study provides further evidence for the prevalence and characteristics of clinical sequelae of COVID‐19 survivors, suggesting long‐term monitoring and management is needed for their full recovery.
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DOI：
10.15557/pimr.2020.0003
发表时间：
2020-01-01
影响因子：
3.6
作者：
通讯作者：
--
DOI：
10.1016/j.cmi.2020.09.023
发表时间：
2021-01
期刊：
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
影响因子：
--
作者：
Xiong Q;Xu M;Li J;Liu Y;Zhang J;Xu Y;Dong W
通讯作者：
Dong W
影响因子：
158.5
作者：
Li, Qun;Guan, Xuhua;Feng, Zijian
通讯作者：
Feng, Zijian
影响因子：
11.1
作者：
Lu, Jing;Peng, Jinju;Ke, Changwen
通讯作者：
Ke, Changwen
影响因子：
13.8
作者：
Bellan M;Soddu D;Balbo PE;Baricich A;Zeppegno P;Avanzi GC;Baldon G;Bartolomei G;Battaglia M;Battistini S;Binda V;Borg M;Cantaluppi V;Castello LM;Clivati E;Cisari C;Costanzo M;Croce A;Cuneo D;De Benedittis C;De Vecchi S;Feggi A;Gai M;Gambaro E;Gattoni E;Gramaglia C;Grisafi L;Guerriero C;Hayden E;Jona A;Invernizzi M;Lorenzini L;Loreti L;Martelli M;Marzullo P;Matino E;Panero A;Parachini E;Patrucco F;Patti G;Pirovano A;Prosperini P;Quaglino R;Rigamonti C;Sainaghi PP;Vecchi C;Zecca E;Pirisi M
通讯作者：
Pirisi M