Developmental expression of extracellular matrix components in intramuscular connective tissue of bovine semitendinosus muscle
Developmental expression of extracellular matrix components in intramuscular connective tissue of bovine semitendinosus muscle
复制标题
牛半腱肌肌内结缔组织细胞外基质成分的发育表达
DOI：
--
复制
发表时间：
1997
影响因子：
2.3
通讯作者：
Koui Takahashi
中科院分区：
文献类型：
--
作者：
Takanori Nishimura;K. Ojima;A. Hattori;Koui Takahashi
摘要：我们采用间接免疫荧光技术研究了牛半腱肌发育过程中肌内结缔组织中细胞外基质成分的表达模式。 I、III、V 和 VI 型胶原和纤连蛋白位于肌内膜和肌束膜。 IV型胶原蛋白、层粘连蛋白和硫酸乙酰肝素蛋白聚糖(PG)仅存在于肌内膜中，而硫酸皮肤素PG仅存在于肌束膜中。这些成分在半腱肌肌内结缔组织中的定位在牛的产前和产后生长过程中保持不变，表明它们对于形成和维持牛半腱肌肌内膜和肌束膜结构至关重要。另一方面，尽管其他基质成分已经表达，但在新生儿的肌内膜中检测不到核心蛋白聚糖。它在2月龄小牛的肌内膜中轻微表达，并且在6月龄以上的牛的肌内膜中可清楚地检测到。硫酸软骨素 PG 在胎儿和新生犊牛的肌膜中几乎检测不到，并在出生后肌肉发育过程中逐渐出现。这些 PG 似乎与出生后肌内膜和肌束膜的发育密切相关。
Abstract We have investigated the expression patterns of extracellular matrix components in intramuscular connective tissue during the development of bovine semitendinosus muscle by means of indirect immunofluorescence techniques. Types I, III, V, and VI collagen and fibronectin were located in the endomysium and the perimysium. Type IV collagen, laminin, and heparan sulfate proteoglycans (PGs) were exclusively located in the endomysium, and dermatan sulfate PGs existed only in the perimysium. The localization of these components in the intramuscular connective tissue of semitendinosus muscle remained unchanged throughout prenatal and postnatal growth of cattle, suggesting that they are essential for forming and maintaining structures of the endomysium and perimysium in bovine semitendinosus muscle. On the other hand, decorin was undetectable in the endomysium of neonates, although other matrix components were already expressed. It was expressed slightly in the endomysium of 2-month-old calves, and clearly detectable in the endomysium of cattle more than 6 months old. Chondroitin sulfate PGs were barely detectable in the perimysium of fetuses and neonatal calves, and progressively appeared during postnatal development of the muscle. It seems likely that these PGs are closely related to the postnatal development of the endomysium and perimysium.
登录
查看更多内容
DOI：
10.1073/pnas.87.9.3264
发表时间：
1990-05-01
影响因子：
11.1
作者：
EHRIG, K;LEIVO, I;ENGVALL, E
通讯作者：
ENGVALL, E
硫酸乙酰肝素蛋白多糖核心蛋白在人体皮肤和其他基底膜中的分布、超微结构定位和个体发育。
DOI：
10.1177/37.7.2659664
发表时间：
1989
期刊：
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
影响因子：
--
作者：
Horiguchi,Y;Couchman,JR;Ljubimov,AV;Yamasaki,H;Fine,JD
通讯作者：
Fine,JD
影响因子：
3.2
作者：
HAYASHI, K;HAYASHI, M;BERNFIELD, M
通讯作者：
BERNFIELD, M
硫酸乙酰肝素介导的上皮细胞表面蛋白多糖与血小板反应蛋白的结合。
DOI：
--
发表时间：
1989
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
Sun,X;Mosher,DF;Rapraeger,A
通讯作者：
Rapraeger,A
来自小鼠乳腺上皮细胞的细胞表面蛋白聚糖含有硫酸软骨素和硫酸乙酰肝素糖胺聚糖。
DOI：
--
发表时间：
1985
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
Rapraeger,A;Jalkanen,M;Endo,E;Koda,J;Bernfield,M
通讯作者：
Bernfield,M