Validation of one-week reliable change methods in cognitively intact community-dwelling older adults.
Validation of one-week reliable change methods in cognitively intact community-dwelling older adults.
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DOI：
10.1080/13825585.2020.1787942
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发表时间：
2021-05
期刊：
影响因子：
--
通讯作者：
Duff K
中科院分区：
文献类型：
--
作者：
Hammers DB;Suhrie KR;Dixon A;Porter S;Duff K
可靠的变更方法可以帮助确定观察到的绩效变化是否有意义。当前的研究试图使用认知完整的老年人样本来验证先前发布的基于标准化回归（SRB）方程的常用认知测试，并通过纳入已知可预测认知表现的相关人口统计和测试相关变量来扩展研究结果。这项研究将 SRB 预测方程应用于 107 名认知完好的老年人，一周内对其进行了两次评估。预测方程也通过将当前验证样本与来自 Duff 原始开发样本的 93 名认知完整的参与者合并来更新，以创建组合开发样本。大多数措施的观察到的基线分数和后续分数之间都有显着改善。然而，观察到的后续分数与 Duff 的 SRB 算法预测的分数之间几乎没有差异，并且基于 Duff 方程观察到的练习效果水平与预期一致。当从这个组合开发样本中重新计算 SRB 时，预测的随访分数大多与达夫方程相当，但估计的标准误差始终较小。当需要在短时间内重复给药时，这些结果有助于支持 SRB 方程的有效性，以预测这些测量的认知表现。研究结果还强调了扩展 SRB 模型在连续预测后续绩效时的效用，以便对个人层面的可靠变化提供更准确的评估。由于短期练习效果被证明可以每年预测认知表现，因此它们有可能为阿尔茨海默氏症连续体患者的临床决策提供信息。
Reliable change methods can assist determination of whether observed changes in performance are meaningful. The current study sought to validate previously-published standardized regression-based (SRB) equations for commonly-administered cognitive tests using a cognitively-intact sample of older adults, and extend findings by including relevant demographic and test-related variables known to predict cognitive performance. This study applied SRB prediction equations to 107 cognitively-intact older adults assessed twice over one week. Prediction equations were also updated by pooling the current validation sample with 93 cognitively-intact participants from Duff’s original development sample to create a combined development sample. Significant improvements were seen between observed baseline and follow-up scores on most measures. However, few differences were seen between observed follow-up scores and those predicted from Duff’s SRB algorithms, and the level of practice effects observed based on Duff’s equations were consistent with expectations. When SRBs were re-calculated from this combined development sample, predicted follow-up scores were mostly comparable with Duff’s equations, but standard errors of the estimate were consistently smaller. These results help support validity of SRB equations to predict cognitive performance on these measures when repeated administration is necessary over short intervals. Findings also highlight the utility of expanding SRB models when predicting follow-up performance serially to provide more accurate assessment of reliable change at the level of the individual. As short-term practice effects are shown to predict cognitive performance annually, they possess the potential to inform clinical decision making about individuals along the Alzheimer’s continuum.
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影响因子：
7.2
作者：
Duff, Kevin;Lyketsos, Constantine G.;McCaffrey, Robert J.
通讯作者：
McCaffrey, Robert J.
影响因子：
9.9
作者：
Darby, D;Maruff, P;McStephen, M
通讯作者：
McStephen, M
影响因子：
3.9
作者：
Attix, Deborah K.;Story, Tyler J.;Barth, Jeffrey T.
通讯作者：
Barth, Jeffrey T.
影响因子：
2.4
作者：
Goodwill, Alicia M.;Campbell, Stephen;Szoeke, Cassandra
通讯作者：
Szoeke, Cassandra
影响因子：
2.6
作者：
Duff, K;Schoenberg, MR;Adams, RL
通讯作者：
Adams, RL