Coagulation abnormalities and their neuro-ophthalmologic manifestations.
Coagulation abnormalities and their neuro-ophthalmologic manifestations.
复制标题
凝血异常及其神经眼科表现。
DOI：
10.1097/00055735-199912000-00004
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发表时间：
1999
影响因子：
3.7
通讯作者：
V. Biousse
中科院分区：
文献类型：
--
作者：
V. Biousse
先天性和获得性高凝状态源于促凝血剂和抗凝血剂之间的不平衡。虽然这些情况在整个血管树中都存在，但它们通常会在离散的静脉或动脉段引起局部血栓病变；这表明血管壁或血流中的局灶性缺陷必须与高凝状态相关才能产生血栓。在过去的几年里，许多与高凝状态相关的新因素被描述出来。本文回顾了先天性和获得性高凝状态，重点介绍了涉及眼睛和中枢神经系统的局灶性血栓形成的最新数据。
Congenital and acquired hypercoagulable states arise from an imbalance between procoagulant and anticoagulant forces. Although these conditions are present throughout the vascular tree, they typically give rise to local thrombotic lesions in discrete segments of the veins or arteries; this suggests that focal defects in the vascular wall or blood flow must be associated with a hypercoagulable state to produce thrombosis. Numerous new factors associated with hypercoagulability have been described in the past few years. Congenital and acquired hypercoagulable states are reviewed here, with an emphasis on recent data on focal thrombosis involving the eye and central nervous system.
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