Microfluidic High-Throughput Platforms for Discovery of Novel Materials.
Microfluidic High-Throughput Platforms for Discovery of Novel Materials.
复制标题
用于发现新材料的微流控高通量平台
DOI：
10.3390/nano10122514
复制
发表时间：
2020-12-15
期刊：
影响因子：
--
通讯作者：
Zhou J
中科院分区：
文献类型：
--
作者：
Zhou P;He J;Huang L;Yu Z;Su Z;Shi X;Zhou J
高通量筛选是加速新材料发现和开发的有力技术。通过并行执行大规模合成和表征过程，它可以快速发现具有所需组分，结构和功能的材料。在高通量筛选的各种方法中，微流控平台引起了越来越多的关注。与目前许多通常基于机器人分配器和自动微孔板的策略相比，微流体平台可以显著提高通量并将试剂的消耗降低几个数量级。本文首先介绍了基于微阵列和微滴的两类微流控高通量平台的研究进展。然后，利用这些平台筛选不同类型的材料，包括无机金属，金属合金和有机聚合物的详细描述。最后，在这个充满希望的领域的挑战和机遇进行了批判性的讨论。
High-throughput screening is a potent technique to accelerate the discovery and development of new materials. By performing massive synthesis and characterization processes in parallel, it can rapidly discover materials with desired components, structures and functions. Among the various approaches for high-throughput screening, microfluidic platforms have attracted increasing attention. Compared with many current strategies that are generally based on robotic dispensers and automatic microplates, microfluidic platforms can significantly increase the throughput and reduce the consumption of reagents by several orders of magnitude. In this review, we first introduce current advances of the two types of microfluidic high-throughput platforms based on microarrays and microdroplets, respectively. Then the utilization of these platforms for screening different types of materials, including inorganic metals, metal alloys and organic polymers are described in detail. Finally, the challenges and opportunities in this promising field are critically discussed.
影响因子：
1.7
作者：
Hook, Andrew L.;Scurr, David J.;Anderson, Daniel G.;Langer, Robert;Williams, Paul;Davies, Martyn;Alexander, Morgan
通讯作者：
Alexander, Morgan