Simultaneous EEG-fMRI reveals attention-dependent coupling of early face processing with a distributed cortical network.

Simultaneous EEG-fMRI reveals attention-dependent coupling of early face processing with a distributed cortical network.
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DOI:
10.1016/j.biopsycho.2017.12.002
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发表时间:
2018-03
影响因子:
2.6
通讯作者:
Johnstone T
Johnstone T
中科院分区:
医学3区
文献类型:
--
作者:
Bayer M;Rubens MT;Johnstone T

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分布皮层激活面协变与ERP早在100毫秒。协变依赖于持续的注意力和逐个试验的认知冲突。自上而下的门控可能适用于比以前已知的更早的视觉处理阶段。视觉处理的速度是我们理解面部感知的核心。然而,在分布式人脸处理网络中,早期视觉处理在多大程度上影响后期处理,以及这种自下而上效应的自上而下调制,仍然不清楚。我们使用同步EEG-fMRI调查皮层活动,显示独特的共变与ERP组件的面孔处理(C1,P1,N170,P3),而操纵持续的注意力和短暂的认知冲突采用情绪化的脸字Stroop任务。刺激后100 ms内的视觉处理的ERP标记物显示与大脑激活的协变,在前楔,后扣带回,左颞中回,左额下回和额盖,和左侧顶枕外侧集群,说明早期处理的影响高阶机制。至关重要的是,这种协变依赖于持续的注意力集中,不一致的试验是不存在的,这表明灵活的自上而下的自下而上的处理门控。
Distributed cortical activation to faces covaries with ERPs as early as 100 ms. Covariations depend on both sustained attention and trial-by-trial cognitive conflict. Top-down gating might apply to earlier visual processing stages than previously known. The speed of visual processing is central to our understanding of face perception. Yet the extent to which early visual processing influences later processing in distributed face processing networks, and the top-down modulation of such bottom-up effects, remains unclear. We used simultaneous EEG-fMRI to investigate cortical activity that showed unique covariation with ERP components of face processing (C1, P1, N170, P3), while manipulating sustained attention and transient cognitive conflict employing an emotional face-word Stroop task. ERP markers of visual processing within 100 ms after stimulus onset showed covariation with brain activation in precuneous, posterior cingulate gyrus, left middle temporal gyrus, left inferior frontal gyrus and frontal operculum, and a left lateral parietal-occipital cluster, illustrating the impact of early stage processing on higher-order mechanisms. Crucially, this covariation depended on sustained attentional focus and was absent for incongruent trials, suggesting flexible top-down gating of bottom-up processing.
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