NMR chemical shift assignments of RNA oligonucleotides to expand the RNA chemical shift database
NMR chemical shift assignments of RNA oligonucleotides to expand the RNA chemical shift database
复制标题
RNA 寡核苷酸的 NMR 化学位移分配以扩展 RNA 化学位移数据库
DOI:
10.1007/s12104-021-10049-0
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发表时间:
2021
影响因子:
0.9
通讯作者:
Morgenstern, Nicholas W.
中科院分区:
文献类型:
--
作者:
Liu, Yaping;Kotar, Anita;Hodges, Tracy L.;Abdallah, Kyrillos;Taleb, Mallak H.;Bitterman, Brayden A.;Jaime, Sara;Schaubroeck, Kyle J.;Mathew, Ethan;Morgenstern, Nicholas W.
RNAs play myriad functional and regulatory roles in the cell. Despite their significance, three-dimensional structure elucidation of RNA molecules lags significantly behind that of proteins. NMR-based studies are often rate-limited by the assignment of chemical shifts. Automation of the chemical shift assignment process can greatly facilitate structural studies, however, accurate chemical shift predictions rely on a robust and complete chemical shift database for training. We searched the Biological Magnetic Resonance Data Bank (BMRB) to identify sequences that had no (or limited) chemical shift information. Here, we report the chemical shift assignments for 12 RNA hairpins designed specifically to help populate the BMRB.
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DOI:
--
发表时间:
2015
期刊:
Journal of magnetic resonance (San Diego, Calif. 1997 : Print)
影响因子:
--
作者:
K. S. Ng;S. L. Lam
通讯作者:
S. L. Lam
DOI:
--
发表时间:
2014-09
期刊:
arXiv: Chemical Physics
影响因子:
--
作者:
A. S. Larsen
通讯作者:
A. S. Larsen
影响因子:
--
作者:
Burnett JC;Rossi JJ
通讯作者:
Rossi JJ
影响因子:
5.6
作者:
P. Legault;C. G. Hoogstraten;E. Metlitzky;A. Pardi
通讯作者:
A. Pardi
影响因子:
2.7
作者:
JOHNSON, BA;BLEVINS, RA
通讯作者:
BLEVINS, RA