Vinculin and metavinculin: oligomerization and interactions with F-actin.
Vinculin and metavinculin: oligomerization and interactions with F-actin.
复制标题
纽蛋白和美纽蛋白:寡聚化以及与 F-肌动蛋白的相互作用。
DOI:
10.1016/j.febslet.2013.02.042
复制
发表时间:
2013
期刊:
影响因子:
3.5
通讯作者:
Campbell,SharonL
中科院分区:
文献类型:
--
作者:
Thompson,PeterM;Tolbert,CaitlinE;Campbell,SharonL
Vinculin, and its splice variant metavinculin, are scaffolding proteins that localize to cellular adhesions. Vinculin is a key player in mediating cell adhesion, motility, and cellular response to force. In the past decade, a number of new studies have evaluated the importance of vinculin oligomers, especially in their role of bundling F-actin. Emerging evidence also suggests that vinculin oligomerization is important for vinculin’s scaffolding function. Here we describe the latest findings on vinculin’s interaction with F-actin and we clarify the different known vinculin oligomers. Differences in these functions between vinculin and metavinculin provide key insights to the structure and function of these oligomers, and should guide further studies.
登录
查看更多内容
DOI:
10.1016/0002-9343(81)90144-3
发表时间:
1981
期刊:
The American journal of medicine
影响因子:
--
作者:
Weksler,BB;Nachman,RL
通讯作者:
Nachman,RL
DOI:
10.1172/jci110378
发表时间:
1981
期刊:
The Journal of clinical investigation
影响因子:
--
作者:
Lehrer,RI;Cohen,L
通讯作者:
Cohen,L
影响因子:
7.5
作者:
Cech,P;Rosove,MH;Harwig,SS;Lehrer,RI
通讯作者:
Lehrer,RI
DOI:
10.1016/s0021-9258(18)34459-4
发表时间:
1982-07
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
M. Castagna;Y. Takai;K. Kaibuchi;K. Sano;U. Kikkawa;Y. Nishizuka
通讯作者:
M. Castagna;Y. Takai;K. Kaibuchi;K. Sano;U. Kikkawa;Y. Nishizuka
影响因子:
--
作者:
Diamond, L;O'Brien, T G;Baird, W M
通讯作者:
Baird, W M