Motility and chemotaxis in Campylobacter and Helicobacter .
Motility and chemotaxis in Campylobacter and Helicobacter .
复制标题
DOI:
10.1146/annurev-micro-090110-102908
复制
发表时间:
2011
影响因子:
10.5
通讯作者:
Hendrixson DR
中科院分区:
文献类型:
--
作者:
Lertsethtakarn P;Ottemann KM;Hendrixson DR
Flagellar motility of Campylobacter jejuni and Helicobacter pylori influences host colonization by promoting migration through viscous milieus such as gastrointestinal mucus. This review explores mechanisms C. jejuni and H. pylori employ to control flagellar biosynthesis and chemotactic responses. These microbes tightly control the activities of σ54 and σ28 to mediate ordered flagellar gene expression. In addition to phase-variable and posttranslational mechanisms, flagellar biosynthesis is regulated spatially and numerically so that only a certain number of organelles are placed at polar sites. To mediate chemotaxis, C. jejuni and H. pylori combine basic chemotaxis signal transduction components with several accessory proteins. H. pylori is unusual in that it lacks a methylation-based adaptation system and produces multiple CheV coupling proteins. Chemoreceptors in these bacteria contain nonconserved ligand binding domains, with several chemoreceptors matched to environmental signals. Together, these mechanisms allow for swimming motility that is essential for colonization.
登录
查看更多内容
影响因子:
3.2
作者:
Dasgupta, N;Ramphal, R
通讯作者:
Ramphal, R
影响因子:
3.2
作者:
Beier, D;Spohn, G;Scarlato, V
通讯作者:
Scarlato, V
DOI:
10.1073/pnas.0502040102
发表时间:
2005-06-28
影响因子:
11.1
作者:
Andersen-Nissen, E;Smith, KD;Aderem, A
通讯作者:
Aderem, A
影响因子:
3.6
作者:
Elliott KT;Dirita VJ
通讯作者:
Dirita VJ
影响因子:
3.2
作者:
Correa, NE;Peng, F;Klose, KE
通讯作者:
Klose, KE