Changing epidemiology of yellow fever virus in Oyo State, Nigeria.
Changing epidemiology of yellow fever virus in Oyo State, Nigeria.
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DOI：
10.1186/s12889-022-12871-0
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发表时间：
2022-03-08
影响因子：
4.5
通讯作者：
Olanike OS
中科院分区：
文献类型：
--
作者：
Bassey BE;Braka F;Onyibe R;Kolude OO;Oluwadare M;Oluwabukola A;Omotunde O;Iyanda OA;Tella AA;Olanike OS
黄热病是一种急性病毒性出血性疾病，流行于热带非洲和拉丁美洲，通过受感染的蚊子传播。尼日利亚最早的黄热病暴发是1864年在拉各斯报告的，随后的定期暴发一直持续到1996年。继前一年尼日利亚东部发生黄热病疫情后，1987年4月和5月在奥约州发生了大规模黄热病疫情。21年来，直到2017年9月才报告进一步确诊病例，此后尼日利亚一直在应对连续爆发的疫情。在尼日利亚再次爆发黄热病疫情之前，全球出现了报告趋势，其他非洲国家也出现了这种趋势。黄热病无法治愈，但通过接种疫苗和媒介控制来控制黄热病。世卫组织于2017年制定了消除黄热病疫情(眼)战略，以改善高危国家对黄热病疫情的预防、准备、检测、管理和应对，并于2018年4月在尼日利亚启动。然而，疫苗接种覆盖率低仍然是一个令人担忧的问题。我们进行了一项回溯性横断面研究，调查了2013-2020年尼日利亚奥约州黄热病病例和暴发的死灰复燃情况。黄热病监测和常规扩大免疫计划(EPI)的数据是审查的重点。监测数据是从国家数据库中检索的，所有33个地方政府评估机构都报告了监测数据，这些数据由国家维护，并得到世界卫生组织在区和州两级的支持。常规计划免疫数据从地区卫生信息软件(DHIS_2)检索。对报告至少一例带有血液样本的疑似黄热病病例的地方政府间机构的比例以及在本报告所述期间每年报告的疑似病例数量进行了衡量。我们还评估了确诊病例的趋势和每10万人的发病率。此外，黄热病疑似病例被分成四个年龄组，并评估了他们的疫苗接种情况。将该州每年的黄热病疫苗行政常规接种覆盖率与每年的确诊病例数量进行了比较。2014至2020年间，当地政府至少报告了一例疑似黄热病病例，并采集了血液样本，比例从6.1%至84.9%不等，共记录了9例黄热病确诊病例(8例)和疑似黄热病病例(1例)。然而，2013年至2016年(包括2018年)没有确诊病例，但每10万人的发病率从0%到2013年到2018年呈上升趋势，2019年上升到3.5%，然后在2020年上升到5.6%。在给定时期报告的240例黄热病疑似病例中，观察到93例(39%)接种了黄热病疫苗。总而言之，该州黄热病病毒传播的增加重申了该州黄热病传播的高风险，并强调了需要采取可行的干预措施，如环境卫生，以消除病媒的生态位环境，并提高常规计划免疫覆盖率，以提供人口免疫力。
Yellow Fever is an acute viral hemorrhagic disease endemic in tropical Africa and Latin America and is transmitted through infected mosquitoes. The earliest outbreak of yellow fever in Nigeria was reported in Lagos in 1864 with subsequent regular outbreaks reported until 1996. A large epidemic of yellow fever occurred in Oyo State in April and May 1987 following an epidemic of sylvatic yellow fever in Eastern Nigeria the previous year. For 21 years, no further confirmed cases were reported until September 2017 following which Nigeria has been responding to successive outbreaks. The renewed onset of yellow fever outbreaks in Nigeria followed a global trend of reports and from other African countries. Yellow Fever disease has no cure, but control is through vaccination and vector control. Eliminating Yellow fever Epidemic (EYE) strategy to improve high-risk countries’ prevention, preparedness, detection, management, and response to yellow fever outbreaks was developed by the WHO in 2017 and launched in Nigeria in April 2018. Yet, poor vaccination coverage continues to be a cause for concern. We conducted a retrospective cross-sectional study that examines the resurgence of Yellow fever cases and outbreaks from 2013 to 2020 in Oyo State, Nigeria. The Yellow Fever data for both surveillance and routine Expanded Programme on Immunization (EPI) were the focus of the review. Surveillance data were retrieved from the State’s database reported by all 33 LGAs, maintained by the State and supported by the World Health Organization at the Zonal and State levels. The routine EPI data were retrieved from District Health Information Software (DHIS_2). The proportion of LGAs reporting at least one case of suspected yellow fever with a blood specimen and the number of suspected cases reported for each year within the period under review was measured. We also assessed the trend of confirmed cases and the incidence per 100,000 persons. Also, suspected cases of yellow fever were categorized into four age groups and their vaccination status was assessed. The State’s annual administrative routine vaccination coverage for yellow fever vaccine was compared with the number of confirmed cases for each year. The proportion of LGAs reporting at least a case of suspected yellow fever, with blood samples collected, ranged from 6.1 to 84.9% between 2014 and 2020 while a total of 9 confirmed (8 cases) and probable (1 case) cases of yellow fever were recorded. However, there were no confirmed cases from the year 2013 to 2016, including 2018 but an upward trend of incidence of the disease per 100,000 persons from 0% to 2013 through 2018, to 3.5% in 2019, and then to 5.6% in 2020 was observed. 93 of 240 (39%) suspected yellow fever cases reported during the given period were observed to have received yellow fever vaccine. In conclusion, the increase in the circulation of the yellow fever virus in the state reiterates the state is at a high risk of yellow fever transmission and underlines the need for viable interventions such as environmental hygiene to rid the environment of the disease vector’s ecological niche and improving routine EPI coverage to provide population immunity.
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影响因子：
--
作者：
Ortiz-Martínez Y;Patiño-Barbosa AM;Rodriguez-Morales AJ
通讯作者：
Rodriguez-Morales AJ
DOI：
10.1590/s1678-9946201759002
发表时间：
2017-01-01
期刊：
Revista do Instituto de Medicina Tropical de São Paulo
影响因子：
--
作者：
Miyaji, Karina Takesaki;Avelino-Silva, Vivian Iida;Sartori, Ana Marli Christovam
通讯作者：
Sartori, Ana Marli Christovam
影响因子：
5.5
作者：
Hamlet, Arran;Jean, Kevin;Garske, Tini
通讯作者：
Garske, Tini
影响因子：
56.3
作者：
Shearer, Freya M.;Moyes, Catherine L.;Reiner, Robert C., Jr.
通讯作者：
Reiner, Robert C., Jr.
DOI：
10.1016/0035-9203(89)90518-x
发表时间：
1989-05-01
影响因子：
2.2
作者：
NASIDI, A;MONATH, TP;OYEDIRAN, ABO
通讯作者：
OYEDIRAN, ABO