The importance of population-specific normal database for quantification of myocardial ischemia: comparison between Japanese 360 and 180-degree databases and a US database.
The importance of population-specific normal database for quantification of myocardial ischemia: comparison between Japanese 360 and 180-degree databases and a US database.
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DOI：
10.1007/s12350-009-9049-1
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发表时间：
2009-05
影响因子：
2.4
通讯作者：
Kinuya, Seigo
中科院分区：
文献类型：
--
作者：
Nakajima, Kenichi;Okuda, Koichi;Kawano, Masaya;Matsuo, Shinro;Slomka, Piotr;Germano, Guido;Kinuya, Seigo
关键词：
我们的目的是开发一个日本正常的数据库，为特定的采集条件，比较美国和日本的正常人群，并检查相机旋转角度范围对正常限值的影响。360°（Jp 360）和180°（Jp 180）采集的负荷-静息99 mTc心肌灌注数据库由日本核医学会的工作组活动使用日本患者创建。Cedars Sinai医学中心先前基于美国患者生成了一个标准的180°数据库（US 180）。此外，90例日本患者进行了冠状动脉造影和360°采集的负荷-静息99 mTc灌注研究，以进行验证，并使用上述三个正常数据库集通过QOS软件进行定量评价。US 180和Jp 360数据库之间的主要差异见于女性的心尖和前壁以及男性的下壁。当通过受试者操作特征分析评价诊断性能时，Jp 360数据库的曲线下面积最高（0.842），其次是Jp 180（0.758）和US 180（0.728）数据库（P = 0.019，Jp 360 vs US 180; P = 0.035，Jp 360 vs Jp 180）。在右冠状动脉狭窄的男性患者中，Jp 360数据库的负荷下冠状动脉区域评分最高（n = 26，Jp360：4.92 ± 4.61 [mean ± SD]，Jp180：4.23 ± 4.29，US180：2.92 ± 3.53; Jp 360和US 180之间的P < .0001），女性左前降支狭窄患者中（n = 12，Jp 360：6.33 ± 4.76，Jp 180：5.25 ± 4.83，US 180：4.50 ± 4.15; Jp 360和US 180之间P = 0.0076）。由于美国和日本正常数据库之间的差异，在使用定量灌注SPECT软件时，必须使用人群和采集特定数据库。
We aimed to develop a Japanese normal database for specific acquisition conditions, to compare US and Japanese normal populations, and to examine effects of camera rotation angle range on the normal limits. Stress-rest 99mTc myocardial perfusion databases for 360° (Jp360) and 180° (Jp180) acquisitions were created by the working group activity of the Japanese Society of Nuclear Medicine using Japanese patients. A standard 180° database (US180) had been previously generated by the Cedars Sinai Medical Center based on American patients. Additionally, 90 Japanese patients underwent coronary arteriography and stress-rest 99mTc perfusion study with 360° acquisition for validation purposes, and quantitative evaluation was performed by QPS software using the above three normal database sets. Major differences between US180 and Jp360 databases were found in the apex and in the anterior wall in females and in the inferior wall in males. When the diagnostic performance was evaluated by receiver-operating characteristic analysis, area under the curve was the highest for Jp360 (0.842), followed by Jp180 (0.758) and US180 (0.728) databases (P = .019, Jp360 vs US180; P = .035, Jp360 vs Jp180). The coronary territory score at stress was highest with the Jp360 database in male patients with right coronary artery stenosis (n = 26, Jp360: 4.92 ± 4.61 [mean ± SD], Jp180: 4.23 ± 4.29, US180: 2.92 ± 3.53; P < .0001 between Jp360 and US180) and in female patients with left anterior descending artery stenosis (n = 12, Jp360: 6.33 ± 4.76, Jp180: 5.25 ± 4.83, US180: 4.50 ± 4.15; P = .0076 between Jp360 and US180). Because of the differences between US and Japanese normal databases, it is essential to use population- and acquisition-specific databases when using quantitative perfusion SPECT software.
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影响因子：
37.8
作者：
Klocke, FJ;Baird, MG;Russell, RO
通讯作者：
Russell, RO
DOI：
10.1007/s00259-006-0321-1
发表时间：
2007-07-01
影响因子：
9.1
作者：
Nakajima, Kenichi;Kusuoka, Hideo;Nishimura, Tsunehiko
通讯作者：
Nishimura, Tsunehiko
影响因子：
2.4
作者：
Slomka, PJ;Nishina, H;Germano, G
通讯作者：
Germano, G
影响因子：
2.6
作者：
Nakajima, Kenichi;Kumita, Shinichiro;Yokozuka, Koichi
通讯作者：
Yokozuka, Koichi
影响因子：
2.4
作者：
Wolak, Arik;Slomka, Piotr J.;Germano, Guido
通讯作者：
Germano, Guido