Interpreting the Tape of Life: Ancestry-Based Analyses Provide Insights and Intuition about Evolutionary Dynamics
Interpreting the Tape of Life: Ancestry-Based Analyses Provide Insights and Intuition about Evolutionary Dynamics
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解释生命的磁带:基于祖先的分析提供了有关进化动力学的见解和直觉
DOI:
10.1162/artl_a_00313
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发表时间:
2020
期刊:
影响因子:
2.6
通讯作者:
Ofria, Charles
中科院分区:
文献类型:
--
作者:
Dolson, Emily;Lalejini, Alexander;Jorgensen, Steven;Ofria, Charles
Fine-scale evolutionary dynamics can be challenging to tease out when focused on the broad brush strokes of whole populations over long time spans. We propose a suite of diagnostic analysis techniques that operate on lineages and phylogenies in digital evolution experiments, with the aim of improving our capacity to quantitatively explore the nuances of evolutionary histories in digital evolution experiments. We present three types of lineage measurements: lineage length, mutation accumulation, and phenotypic volatility. Additionally, we suggest the adoption of four phylogeny measurements from biology: phylogenetic richness, phylogenetic divergence, phylogenetic regularity, and depth of the most-recent common ancestor. In addition to quantitative metrics, we also discuss several existing data visualizations that are useful for understanding lineages and phylogenies: state sequence visualizations, fitness landscape overlays, phylogenetic trees, and Muller plots. We examine the behavior of these metrics (with the aid of data visualizations) in two well-studied computational contexts: (1) a set of two-dimensional, real-valued optimization problems under a range of mutation rates and selection strengths, and (2) a set of qualitatively different environments in the Avida digital evolution platform. These results confirm our intuition about how these metrics respond to various evolutionary conditions and indicate their broad value.
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影响因子:
9.8
作者:
Zaman L;Meyer JR;Devangam S;Bryson DM;Lenski RE;Ofria C
通讯作者:
Ofria C
DOI:
10.1145/3205651.3208301
发表时间:
2018
期刊:
Proceedings of the Genetic and Evolutionary Computation Conference Companion on - GECCO '18
影响因子:
--
作者:
Dolson, Emily;Ofria, Charles
通讯作者:
Ofria, Charles
影响因子:
4.7
作者:
N. Virgo;E. Agmon;Chrisantha Fernando
通讯作者:
Chrisantha Fernando
DOI:
10.1145/2464576.2482714
发表时间:
2013
期刊:
Proceedings of the 15th annual conference companion on Genetic and evolutionary computation
影响因子:
--
作者:
Bogdan Burlacu;M. Affenzeller;M. Kommenda;Stephan M. Winkler;G. Kronberger
通讯作者:
G. Kronberger
DOI:
--
发表时间:
2002
期刊:
Computers & graphics
影响因子:
--
作者:
A. V. Dam;D. Laidlaw;R. M. Simpson
通讯作者:
R. M. Simpson